Dasatinib resensitizes BRAF/MEK inhibitor efficacy in patient-derived xenografts from patients with progression on BRAF/MEK inhibitor treatment
达沙替尼可使BRAF/MEK抑制剂在BRAF/MEK抑制剂治疗后病情进展的患者来源的异种移植模型中重新发挥疗效。
期刊:iScience
影响因子:4.1
doi:10.1016/j.isci.2026.114669
Rebecca, Vito W; Xiao, Min; Kossenkov, Andrew; Godok, Tetiana; Brown, Gregory Schuyler; Fingerman, Dylan; Alicea, Gretchen M; Wei, Meihan; Ji, Hongkai; Portuallo, Marie; Bravo, Jeremy; Elad, Vissy; Chen, Yeqing; Toska, Eneda; Fane, Mitchell E; Couts, Kasey L; Villanueva, Jessie; Nathanson, Katherine; Arun, Keerthana M; Warrier, Govind; Yin, Xiangfan; Ding, Jianyi; Liu, Qin; Goyal, Yogesh; Gopal, Y N Vashisht; Davies, Michael A; Herlyn, Meenhard
