Selectivity for TP53 signalling drives the mode of action of a highly potent N,O,O-tridentate naphthoquinone-based organo-ruthenium anticancer drug candidate
一种高效的基于N,O,O-三齿萘醌的有机钌抗癌候选药物的作用机制取决于其对TP53信号通路的选择性。
期刊:Chemical Science
影响因子:7.4
doi:10.1039/d5sc00735f
Rosner, Alexander; Skos, Lukas; Mendrina, Theresa; Baier, Dina; Hejl, Michaela; Borutzki, Yasmin; Gradl, Mathias; Geisler, Heiko; Mohr, Thomas; Legin, Anton; Jakupec, Michael A; Bileck, Andrea; Gerner, Christopher; Koellensperger, Gunda; Heffeter, Petra; Berger, Walter; Keppler, Bernhard K; Kandioller, Wolfgang; Meier-Menches, Samuel M
