日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Neoadjuvant BO-112 and hypofractionated radiation therapy with or without nivolumab in soft tissue sarcoma: preclinical and phase 1 results

新辅助 BO-112 联合或不联合纳武利尤单抗的低分割放射治疗在软组织肉瘤中的应用:临床前和 I 期研究结果

Deng, Jie; Pal, Aastha; Testa, Stefano; Xu, Jingyu W; Tran, Linh M; Graham, Danielle S; Hargil, Aviv; Subramanian, Ajay; Campbell, Katie M; Limsuwannarot, Sam; Chumpitaz Lavalle, Álvaro; Chin, Scott C; Kremer, Sarah; Tariveranmoshabad, Mito; Ewongwo, Agnes; Silvia, Sk Nadia Rahman; Ogana, Heather; Nemat-Gorgani, Neda; Dubinett, Steven M; Jaycox, Jillian R; Felix, Carol; Schaue, Dörthe; Nelson, Scott D; Levine, Benjamin; Motamedi, Kambiz; Ghazikhanian, Varand; Chmielowski, Bartosz; Reddy, Vishruth; Singh, Arun S; Trnkova, Zuzana Jirakova; Good, Zinaida; Quintero, Marisol; Crompton, Joseph G; Bernthal, Nicholas; Eilber, Fritz C; Moding, Everett J; Kalbasi, Anusha

Long-Term Tofersen in SOD1 Amyotrophic Lateral Sclerosis

托弗森治疗SOD1肌萎缩侧索硬化症的长期疗效

Miller, Timothy M; Cudkowicz, Merit E; Shaw, Pamela J; Genge, Angela; Sobue, Gen; Bucelli, Robert C; Chiò, Adriano; Van Damme, Philip; Ludolph, Albert C; Glass, Jonathan D; Andrews, Jinsy A; Babu, Suma; Benatar, Michael; McDermott, Christopher J; Salachas, François; Bruneteau, Gaëlle; Al-Chalabi, Ammar; Amorin, Matthew; Nestorov, Ivan; Graham, Danielle; Lin, Luan; Sun, Peng; McNeill, Manjit; Malek, Sohail; Inra, Jennifer; Garafalo, Steve; Fradette, Stephanie

Identification of tofersen PD-response biomarkers in VALOR clinical trial CSF via multiplexed quantitative proteomics.

通过多重定量蛋白质组学鉴定 VALOR 临床试验脑脊液中托福生帕金森反应生物标志物。

Guise Amanda J, Ferber Kyle L, Young Damon, Edwards Amanda L, Sabouri Somayeh, Fraser Kyle B, Milliman Eric, Plowey Edward D, Zoghbi Jad, Fradette Stephanie M, Graham Danielle L

Neurofilament Proteoforms in Amyotrophic Lateral Sclerosis Are Different in Cerebrospinal Fluid and Blood

肌萎缩侧索硬化症患者的神经丝蛋白异构体在脑脊液和血液中存在差异

Coulton, John B; He, Yingxin; Budelier, Melissa M; Barthélemy, Nicolas; Ireland, Margaret D; Hu, Miwei; Graham, Danielle; Ferguson, Toby; Berry, James D; Bateman, Randall J; Miller, Timothy M; Ly, Cindy V

Central Nervous System Biodistribution and Pharmacokinetics of Radiolabeled Tofersen in Rodents, Nonhuman Primates, and Humans

放射性标记的托福生在啮齿动物、非人灵长类动物和人类中枢神经系统的生物分布和药代动力学

Cook, Brendon E; McLaren, Donald G; Sullivan, Jenna M; El Fakhri, Georges; Yokell, Daniel L; Freeman, Mason W; Currier, Nicolas; Oestergaard, Michael E; Dobson, Howard; Hesterman, Jacob; Salem, Nicolas; Nestorov, Ivan; Monine, Michael; Martarello, Laurent; Evans, Karleyton C; Fradette, Stephanie; Ferguson, Toby A; Graham, Danielle; Passamonti, Luca

SCAN-ACT: adoptive T cell therapy target discovery through single-cell transcriptomics.

SCAN-ACT:通过单细胞转录组学发现过继性T细胞疗法靶点

Testa Stefano, Pal Aastha, Subramanian Ajay, Varma Sushama, Tang Jack Pengfei, Graham Danielle, Arfan Sara, Pan Minggui, Bui Nam Q, Ganjoo Kristen N, Dry Sarah, Huang Paul, van de Rijn Matt, Jiang Wei, Kalbasi Anusha, Moding Everett J

Development of a horizontal transmission model to assess the effects of exposure to pathogenic E. cecorum during the hatching phase in broiler chickens

建立水平传播模型以评估肉鸡孵化期接触致病性盲肠杆菌的影响

Higuita, James; Arango, Marcela; Forga, Aaron; Rowland, Mitch; Liu, Jundi; Wolfenden, Ross; Graham, Danielle

Feasibility of applying Bacillus amyloliquefaciens-derived solid state fermentation products into the hatch cabinet environment as a method to mitigate the microbial bloom during the hatching phase

将枯草芽孢杆菌固态发酵产物应用于孵化柜环境以减轻孵化阶段微生物大量繁殖的可行性研究

Rowland, Mitchell C; Graham, Lucas E; Selby, Callie; Forga, Aaron J; Hargis, Billy M; Vuong, Christine N; Graham, Danielle

2024 White paper on recent issues in bioanalysis: Impact of LDT in US and IVDR in EU; AI/ML for High Parameter Flow Cytometry; The rise of Olink Technology; CDx for AAV Gene Therapies; Integrative Bioanalysis by Multiple Platforms; Super Sensitive ADA/NAb LBA (PART 2A - Recommendations on Advanced Strategies for Biomarkers, IVD/CDx Assays (BAV), Cell Based Assays (CBA), and Ligand-Binding Assays (LBA) PART 2B - Regulatory Agencies' Input on Biomarkers, IVD/CDx, and Biomarker Assay Validation)

2024 年生物分析最新议题白皮书:美国实验室自建检测 (LDT) 和欧盟体外诊断医疗器械法规 (IVDR) 的影响;高参数流式细胞术的 AI/ML;Olink 技术的崛起;腺相关病毒 (AAV) 基因疗法的伴随诊断 (CDx);多平台整合生物分析;超灵敏 ADA/NAb 配体结合分析 (LBA)(第二部分 A - 生物标志物、体外诊断/伴随诊断检测 (BAV)、细胞检测 (CBA) 和配体结合分析 (LBA) 的高级策略建议;第二部分 B - 监管机构对生物标志物、体外诊断/伴随诊断和生物标志物检测验证的意见)

Bivi, Nicoletta; Graham, Danielle; Joglekar, Laura; McGuire, Kristina; Stoop, Jeroen; Zoghbi, Jad; Baker, Brian; Bandukwala, Abbas; Bond, Sarah; Buoninfante, Alessandra; Chen, Jeff; Dysinger, Mark; Engelbergs, Jörg; Fiscella, Michele; Garofolo, Fabio; Hopper, Shirley; Jones, Barry; King, Lindsay; Murphy, Rocio; Palmer, Rachel; Sanderink, Gerard; Seyda, Agnes; Tang, Huaping; Van Tuyl, Andrea; Wagner, Leslie; Walravens, Karl; Wang, Kai; Zander, Hilke; Zhu, Liang; Li, Ming; Lin, Yi-Dong; Natalia, Mahwish; Standifer, Nathan; Eck, Steven; Goihberg, Polina; Grugan, Katharine; Hedrick, Michael Nathan; Hopkins, Greg; Kar, Sumit; Keller, Steve; McGrath, Shannon; O'Gorman, Bill; Stevens, Chad; Stevens, Erin; Terszowski, Grzegorz; Trampont, Paul C; Yao, Shuyu; Joyce, Alison; Kumar, Seema; Owen, Carolina; Pine, Samuel; Yearwood, Graham; Cao, Liching; Clausen, Valerie; Coble, Kelly; Culbert, Andria; Gupta, Shalini; Hughes, Richard; Liu, Susana; Lu, Kun; Martello, Rita; Reese, Kimberly J; Stubenrauch, Kay-Gunnar; Wen, Yi

Size-fractionated metagenomic depth profiles from two sulfidic stations in the Chesapeake Bay

切萨皮克湾两个硫化物站位的按粒径分级的宏基因组深度剖面

Fuchsman, Clara A; Cram, Jacob A; Huntemann, Marcel; Riley, Robert; Foster, Brian; Foster, Bryce; Roux, Simon; Palaniappan, Krishnaveni; Mukherjee, Supratim; Reddy, T B K; Daum, Chris; Copeland, Alex; Chen, I-Min A; Ivanova, Natalia N; Kyrpides, Nikos C; Graham, Danielle; Eloe-Fadrosh, Emiley A; Malkin, Sairah Y