日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Medicinal cannabis plant extract (NTI164) modifies epigenetic, ribosomal, and immune pathways in paediatric acute-onset neuropsychiatric syndrome

药用大麻植物提取物（NTI164）可改变儿童急性起病神经精神综合征的表观遗传、核糖体和免疫通路。

期刊:Neurotherapeutics
影响因子:6.9
doi:10.1016/j.neurot.2025.e00828
Keating, Brooke A; Han, Velda X; Nishida, Hiroya; Aryamanesh, Nader; Marshall, Lee L; Gloss, Brian S; Lau, Xianzhong; Dissanayake, Ruwani; Dervish, Suat; Graham, Mark E; Mohammad, Shekeeb S; Kanhangad, Manoj; Fahey, Michael C; Patel, Shrujna; Dale, Russell C
信号转导
表观遗传
免疫/内分泌
发表日期：2026
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Pyroxd1 is essential for murine viability with the homozygous N155S recurrent variant linked to myopathy, muscle hypotrophy and osteopenia.

Pyroxd1 对小鼠的生存至关重要，纯合 N155S 复发性变异与肌病、肌肉萎缩和骨质减少有关。

期刊:Acta Neuropathologica Communications
影响因子:5.7
doi:10.1186/s40478-026-02259-1
Evesson Frances J, Dziaduch Gregory, Yasa Joe, Best Heather A, Kiriaev Leonit, Pang Ignatius, Jones Vanessa, Kettle Emma, Zhang Katharine, Piper Ann-Katrin, Wark Jesse R, Scott Isaac, Joshi Himanshu, Sutton R Bryan, Tam Patrick P L, Houweling Peter J, Graham Mark E, Yuen Michaela, Lemcket Frances A, Cooper Sandra T
发表日期：2026
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Cumulative environmental exposures adversely impact social behaviour and are associated with dysregulation of genes and proteins involved in epigenetic, ribosomal, and immune regulation in male mice

累积环境暴露会对雄性小鼠的社会行为产生不利影响，并与表观遗传、核糖体和免疫调节相关基因和蛋白质的失调有关。

期刊:Inflammation Research
影响因子:5.4
doi:10.1007/s00011-025-02152-y
Bucknor, Morgan C; Keating, Brooke A; Han, Velda X; Gloss, Brian S; Dey, Pinki; Aryamanesh, Nader; Marshall, Lee L; Graham, Mark E; Dissanayake, Ruwani; Lau, Xianzhong; Patel, Shrujna; Petkova, Stela P; Valtchev, Peter; Gururajan, Anand; Dale, Russell C; Hofer, Markus J
表观遗传
免疫/内分泌
发表日期：2026
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Proteostasis as a fundamental principle of Tau immunotherapy

蛋白质稳态是Tau蛋白免疫疗法的基本原则

期刊:Brain
影响因子:11.7
doi:10.1093/brain/awae254
Cruz, Esteban; Nisbet, Rebecca M; Padmanabhan, Pranesh; van Waardenberg, Ashley J; Graham, Mark E; Nkajja, Godfrey; Tapaswi, Swara; Connor, Bradley J; Robinson, Phil; Götz, Jürgen
蛋白质稳态
免疫/内分泌
发表日期：2025
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Epigenetic, ribosomal, and immune dysregulation in paediatric acute-onset neuropsychiatric syndrome

儿童急性起病神经精神综合征中的表观遗传、核糖体和免疫失调

期刊:Molecular Psychiatry
影响因子:10.1
doi:10.1038/s41380-025-03127-5
Han, Velda X; Alshammery, Sarah; Keating, Brooke A; Gloss, Brian S; Hofer, Markus J; Graham, Mark E; Aryamanesh, Nader; Marshall, Lee L; Yuan, Songyi; Maple-Brown, Emma; Yan, Jingya; Bandodkar, Sushil; Kothur, Kavitha; Nishida, Hiroya; Jones, Hannah; Tsang, Erica; Lau, Xianzhong; Dissanayake, Ruwani; Perkes, Iain; Mohammad, Shekeeb S; Brilot, Fabienne; Gold, Wendy; Patel, Shrujna; Dale, Russell C
表观遗传
免疫/内分泌
发表日期：2025
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Differentiation of brain and retinal organoids from confluent cultures of pluripotent stem cells connected by nerve-like axonal projections of optic origin

由视神经来源的多能干细胞融合培养物分化而来，这些干细胞通过神经样轴突投射相互连接，最终形成脑和视网膜类器官。

期刊:Stem Cell Reports
影响因子:5.1
doi:10.1016/j.stemcr.2022.04.003
Fernando, Milan; Lee, Scott; Wark, Jesse R; Xiao, Di; Lim, Benjamin Y; O'Hara-Wright, Michelle; Kim, Hani J; Smith, Grady C; Wong, Ted; Teber, Erdahl T; Ali, Robin R; Yang, Pengyi; Graham, Mark E; Gonzalez-Cordero, Anai
发育与干细胞
神经科学
干细胞
3D/类器官
细胞生物学
发表日期：2022
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Kruppel-associated Box (KRAB)-associated co-repressor (KAP-1) Ser-473 phosphorylation regulates heterochromatin protein 1β (HP1-β) mobilization and DNA repair in heterochromatin.

Kruppel 相关盒 (KRAB) 相关共抑制因子 (KAP-1) Ser-473 磷酸化调节异染色质蛋白 1β (HP1-β) 的动员和异染色质中的 DNA 修复

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M112.368381
Bolderson Emma, Savage Kienan I, Mahen Robert, Pisupati Venkat, Graham Mark E, Richard Derek J, Robinson Phillip J, Venkitaraman Ashok R, Khanna Kum Kum
免疫/内分泌
磷酸化
发表日期：2012
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Autophosphorylation and ATM activation: additional sites add to the complexity.

自磷酸化和 ATM 激活：其他位点增加了复杂性

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M110.204065
Kozlov Sergei V, Graham Mark E, Jakob Burkhard, Tobias Frank, Kijas Amanda W, Tanuji Marcel, Chen Philip, Robinson Phillip J, Taucher-Scholz Gisela, Suzuki Keiji, So Sairai, Chen David, Lavin Martin F
表观遗传
磷酸化
发表日期：2011
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Calcineurin selectively docks with the dynamin Ixb splice variant to regulate activity-dependent bulk endocytosis.

钙调磷酸酶选择性地与动力蛋白 Ixb 剪接变体结合，以调节活性依赖性大体积内吞作用

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M111.273110
Xue Jing, Graham Mark E, Novelle Aimee E, Sue Nancy, Gray Noah, McNiven Mark A, Smillie Karen J, Cousin Michael A, Robinson Phillip J
其它
发表日期：2011
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Involvement of novel autophosphorylation sites in ATM activation

ATM激活过程中新型自磷酸化位点的参与

期刊:EMBO Journal
影响因子:8.3
doi:10.1038/sj.emboj.7601231
Kozlov, Sergei V; Graham, Mark E; Peng, Cheng; Chen, Philip; Robinson, Phillip J; Lavin, Martin F
信号转导
磷酸化
ATM
发表日期：2006
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