Graham Neil M H相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Dupilumab efficacy in adolescents with uncontrolled, moderate-to-severe asthma: LIBERTY ASTHMA QUEST

Dupilumab治疗未控制的中重度哮喘青少年患者的疗效：LIBERTY ASTHMA QUEST研究

影响因子:12

doi:10.1111/all.14872

Maspero, Jorge F; FitzGerald, John Mark; Pavord, Ian D; Rice, Megan S; Maroni, Jaman; Rowe, Paul J; Pirozzi, Gianluca; Amin, Nikhil; Ruddy, Marcella; Graham, Neil M H; Teper, Ariel; Hardin, Megan

发表日期：2021

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Conjunctivitis in Dupilumab Clinical Trials for Adolescents with Atopic Dermatitis or Asthma

杜普利尤单抗治疗青少年特应性皮炎或哮喘临床试验中的结膜炎

期刊:American Journal of Clinical Dermatology

影响因子:8.8

doi:10.1007/s40257-020-00577-1

Bansal, Ashish; Simpson, Eric L; Paller, Amy S; Siegfried, Elaine C; Blauvelt, Andrew; de Bruin-Weller, Marjolein; Corren, Jonathan; Sher, Lawrence; Guttman-Yassky, Emma; Chen, Zhen; Daizadeh, Nadia; Kamal, Mohamed A; Shumel, Brad; Mina-Osorio, Paola; Mannent, Leda; Patel, Naimish; Graham, Neil M H; Khokhar, Faisal A; Ardeleanu, Marius

发表日期：2021

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Dupilumab suppresses type 2 inflammatory biomarkers across multiple atopic, allergic diseases.

Dupilumab 可抑制多种特应性过敏性疾病中的 2 型炎症生物标志物

期刊:Clinical and Experimental Allergy

影响因子:5.2

doi:10.1111/cea.13954

Hamilton Jennifer D, Harel Sivan, Swanson Brian N, Brian William, Chen Zhen, Rice Megan S, Amin Nikhil, Ardeleanu Marius, Radin Allen, Shumel Brad, Ruddy Marcella, Patel Naimish, Pirozzi Gianluca, Mannent Leda, Graham Neil M H

发表日期：2021

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Dupilumab Significantly Modulates Pain and Discomfort in Patients With Atopic Dermatitis: A Post Hoc Analysis of 5 Randomized Clinical Trials

度普利尤单抗显著调节特应性皮炎患者的疼痛和不适：5项随机临床试验的事后分析

doi:10.1097/DER.0000000000000698

Silverberg, Jonathan I; Simpson, Eric L; Guttman-Yassky, Emma; Cork, Michael J; de Bruin-Weller, Marjolein; Yosipovitch, Gil; Eckert, Laurent; Chen, Zhen; Ardeleanu, Marius; Shumel, Brad; Hultsch, Thomas; Rossi, Ana B; Hamilton, Jennifer D; Orengo, Jamie M; Ruddy, Marcella; Graham, Neil M H; Pirozzi, Gianluca; Gadkari, Abhijit

发表日期：2021

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Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis: A Phase 3 Randomized Clinical Trial

Dupilumab治疗未控制的中重度特应性皮炎青少年患者的疗效和安全性：一项3期随机临床试验

期刊:Jama Dermatology

影响因子:11

doi:10.1001/jamadermatol.2019.3336

Simpson, Eric L; Paller, Amy S; Siegfried, Elaine C; Boguniewicz, Mark; Sher, Lawrence; Gooderham, Melinda J; Beck, Lisa A; Guttman-Yassky, Emma; Pariser, David; Blauvelt, Andrew; Weisman, Jamie; Lockshin, Benjamin; Hultsch, Thomas; Zhang, Qin; Kamal, Mohamed A; Davis, John D; Akinlade, Bolanle; Staudinger, Heribert; Hamilton, Jennifer D; Graham, Neil M H; Pirozzi, Gianluca; Gadkari, Abhijit; Eckert, Laurent; Stahl, Neil; Yancopoulos, George D; Ruddy, Marcella; Bansal, Ashish

发表日期：2020

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Efficacy and Safety of Multiple Dupilumab Dose Regimens After Initial Successful Treatment in Patients With Atopic Dermatitis: A Randomized Clinical Trial

特应性皮炎患者初始治疗成功后，多种度普利尤单抗给药方案的疗效和安全性：一项随机临床试验

期刊:Jama Dermatology

影响因子:11

doi:10.1001/jamadermatol.2019.3617

Worm, Margitta; Simpson, Eric L; Thaçi, Diamant; Bissonnette, Robert; Lacour, Jean-Philippe; Beissert, Stefan; Kawashima, Makoto; Ferrándiz, Carlos; Smith, Catherine H; Beck, Lisa A; Chan, Kuo-Chen; Chen, Zhen; Akinlade, Bolanle; Hultsch, Thomas; Staudinger, Heribert; Gadkari, Abhijit; Eckert, Laurent; Davis, John D; Rajadhyaksha, Manoj; Graham, Neil M H; Pirozzi, Gianluca; Stahl, Neil; Yancopoulos, George D; Ardeleanu, Marius

发表日期：2020

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Association of High Serum Interleukin-6 Levels With Severe Progression of Rheumatoid Arthritis and Increased Treatment Response Differentiating Sarilumab From Adalimumab or Methotrexate in a Post Hoc Analysis

事后分析显示，高血清白细胞介素-6水平与类风湿性关节炎的严重进展和治疗反应增强相关，并能区分沙利鲁单抗与阿达木单抗或甲氨蝶呤。

期刊:Arthritis & Rheumatology

影响因子:10.9

doi:10.1002/art.41299

Boyapati, Anita; Schwartzman, Sergio; Msihid, Jérôme; Choy, Ernest; Genovese, Mark C; Burmester, Gerd R; Lam, Gordon; Kimura, Toshio; Sadeh, Jonathan; Weinreich, David M; Yancopoulos, George D; Graham, Neil M H

细胞生物学

发表日期：2020

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Clinically Meaningful Responses to Dupilumab in Adolescents with Uncontrolled Moderate-to-Severe Atopic Dermatitis: Post-hoc Analyses from a Randomized Clinical Trial

Dupilumab治疗未控制的中重度特应性皮炎青少年患者的临床意义反应：一项随机临床试验的事后分析

期刊:American Journal of Clinical Dermatology

影响因子:8.8

doi:10.1007/s40257-019-00478-y

Paller, Amy S; Bansal, Ashish; Simpson, Eric L; Boguniewicz, Mark; Blauvelt, Andrew; Siegfried, Elaine C; Guttman-Yassky, Emma; Hultsch, Thomas; Chen, Zhen; Mina-Osorio, Paola; Lu, Yufang; Rossi, Ana B; He, Xinyi; Kamal, Mohamed; Graham, Neil M H; Pirozzi, Gianluca; Ruddy, Marcella; Eckert, Laurent; Gadkari, Abhijit

发表日期：2020

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Dupilumab Provides Favorable Safety and Sustained Efficacy for up to 3 Years in an Open-Label Study of Adults with Moderate-to-Severe Atopic Dermatitis

在一项针对中重度特应性皮炎成年患者的开放标签研究中，度普利尤单抗显示出良好的安全性和长达3年的持续疗效。

期刊:American Journal of Clinical Dermatology

影响因子:8.8

doi:10.1007/s40257-020-00527-x

Beck, Lisa A; Thaçi, Diamant; Deleuran, Mette; Blauvelt, Andrew; Bissonnette, Robert; de Bruin-Weller, Marjolein; Hide, Michihiro; Sher, Lawrence; Hussain, Iftikhar; Chen, Zhen; Khokhar, Faisal A; Beazley, Bethany; Ruddy, Marcella; Patel, Naimish; Graham, Neil M H; Ardeleanu, Marius; Shumel, Brad

发表日期：2020

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IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis

Dupilumab 阻断 IL-4Rα 可减少金黄色葡萄球菌定植并增加特应性皮炎的微生物多样性

期刊:Journal of Investigative Dermatology

影响因子:5.7

doi:10.1016/j.jid.2019.05.024

Callewaert, Chris; Nakatsuji, Teruaki; Knight, Rob; Kosciolek, Tomasz; Vrbanac, Alison; Kotol, Paul; Ardeleanu, Marius; Hultsch, Thomas; Guttman-Yassky, Emma; Bissonnette, Robert; Silverberg, Jonathan I; Krueger, James; Menter, Alan; Graham, Neil M H; Pirozzi, Gianluca; Hamilton, Jennifer D; Gallo, Richard L

发表日期：2020

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