日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

The development of a PET radiotracer for imaging alpha synuclein aggregates in Parkinson's disease

开发用于帕金森病中α-突触核蛋白聚集体成像的PET放射性示踪剂

期刊:RSC Medicinal Chemistry
影响因子:3.6
doi:10.1039/d5md00057b
Tian, Gui-Long; Hsieh, Chia-Ju; Guarino, Dinahlee Saturnino; Graham, Thomas J A; Lengyel-Zhand, Zsofia; Schmitz, Alexander; Chia, Wai Kit; Young, Anthony J; Crosby, John-Grey; Plakas, Konstantinos; Huang, Tianyu; Jiang, Hao; Yu, Yanbo; Hou, Catherine; Lee, Hsiaoju; Petersson, E James; Giannakoulias, Sam; O'Shea, Jennifer; Kotzbauer, Paul; Tu, Zhude; Mathis, Chester A; Mach, Robert H
帕金森
神经科学
发表日期：2025
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A Small-molecule Antagonist Radiotracer for Positron Emission Tomography Imaging of the Mu Opioid Receptor

用于μ阿片受体正电子发射断层扫描成像的小分子拮抗剂放射性示踪剂

期刊:
影响因子:
doi:10.1101/2024.10.12.618019
Plakas, Konstantinos; Hsieh, Chia-Ju; Guarino, Dinahlee Saturnino; Hou, Catherine; Chia, Wai-Kit; Young, Anthony; Schmitz, Alexander; Ho, Yi-Pei; Weng, Chi-Chang; Lee, Hsiaoju; Li, Shihong; Graham, Thomas J A; Mach, Robert H
信号转导
发表日期：2024
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In Silico Discovery and Subsequent Characterization of Potent 4R-Tauopathy Positron Emission Tomography Radiotracers

利用计算机模拟发现并表征强效的4R-tau蛋白病正电子发射断层扫描放射性示踪剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.3c00775
Graham, Thomas J A; Lindberg, Anton; Tong, Junchao; Stehouwer, Jeffrey S; Vasdev, Neil; Mach, Robert H; Mathis, Chester A
发表日期：2023
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Screening of σ(2) Receptor Ligands and In Vivo Evaluation of (11)C-Labeled 6,7-Dimethoxy-2-[4-(4-methoxyphenyl)butan-2-yl]-1,2,3,4-tetrahydroisoquinoline for Potential Use as a σ(2) Receptor Brain PET Tracer

筛选σ(2)受体配体并体内评价(11)C标记的6,7-二甲氧基-2-[4-(4-甲氧基苯基)丁-2-基]-1,2,3,4-四氢异喹啉作为σ(2)受体脑PET示踪剂的潜在用途

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.2c00191
Kim, Ho Young; Lee, Ji Youn; Hsieh, Chia-Ju; Riad, Aladdin; Izzo, Nicholas J; Catalano, Susan M; Graham, Thomas J A; Mach, Robert H
信号转导
神经科学
发表日期：2022
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Metallaphotoredox aryl and alkyl radiomethylation for PET ligand discovery

金属光氧化还原芳基和烷基放射性甲基化用于PET配体发现

期刊:Nature
影响因子:48.5
doi:10.1038/s41586-020-3015-0
Pipal, Robert W; Stout, Kenneth T; Musacchio, Patricia Z; Ren, Sumei; Graham, Thomas J A; Verhoog, Stefan; Gantert, Liza; Lohith, Talakad G; Schmitz, Alexander; Lee, Hsiaoju S; Hesk, David; Hostetler, Eric D; Davies, Ian W; MacMillan, David W C
表观遗传
发表日期：2021
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Structure-activity relationship studies and bioactivity evaluation of 1,2,3-triazole containing analogues as a selective sphingosine kinase-2 inhibitors.

1,2,3-三唑类似物作为选择性鞘氨醇激酶-2抑制剂的结构活性关系研究和生物活性评价

期刊:European Journal of Medicinal Chemistry
影响因子:5.9
doi:10.1016/j.ejmech.2020.112713
Tangadanchu Vijai Kumar Reddy, Jiang Hao, Yu Yanbo, Graham Thomas J A, Liu Hui, Rogers Buck E, Gropler Robert, Perlmutter Joel, Tu Zhude
其它
发表日期：2020
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Chalcones and Five-Membered Heterocyclic Isosteres Bind to Alpha Synuclein Fibrils in Vitro

查尔酮和五元杂环等排体在体外与α-突触核蛋白原纤维结合

期刊:ACS Omega
影响因子:4.3
doi:10.1021/acsomega.7b01897
Hsieh, Chia-Ju; Xu, Kuiying; Lee, Iljung; Graham, Thomas J A; Tu, Zhude; Dhavale, Dhruva; Kotzbauer, Paul; Mach, Robert H
神经科学
发表日期：2018
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Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules

α-突触核蛋白原纤维含有多个小分子结合位点

期刊:ACS Chemical Neuroscience
影响因子:3.9
doi:10.1021/acschemneuro.8b00177
Hsieh, Chia-Ju; Ferrie, John J; Xu, Kuiying; Lee, Iljung; Graham, Thomas J A; Tu, Zhude; Yu, Jennifer; Dhavale, Dhruva; Kotzbauer, Paul; Petersson, E James; Mach, Robert H
神经科学
发表日期：2018
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Correction to Intercepting Wacker Intermediates with Arenes: CH Functionalization and Dearomatization

对“用芳烃截获Wacker中间体：CH官能化和脱芳构化”的更正

期刊:Organic Letters
影响因子:5
doi:10.1021/ol4031364
Shields, Jason D; Ahneman, Derek T; Graham, Thomas J A; Doyle, Abigail G
发表日期：2012
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Nickel-catalyzed cross-coupling of chromene acetals and boronic acids

镍催化的色烯缩醛与硼酸的交叉偶联反应

期刊:Organic Letters
影响因子:5
doi:10.1021/ol300364s
Graham, Thomas J A; Doyle, Abigail G
发表日期：2012
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