日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Variants on the UBE2L3/YDJC Autoimmune Disease Risk Haplotype Increase UBE2L3 Expression by Modulating CCCTC-Binding Factor and YY1 Binding

UBE2L3/YDJC 自身免疫性疾病风险单倍型的变异通过调节 CCCTC 结合因子和 YY1 结合来增加 UBE2L3 表达

Jaanam Gopalakrishnan, Kandice L Tessneer, Yao Fu, Satish Pasula, Richard C Pelikan, Jennifer A Kelly, Graham B Wiley, Patrick M Gaffney

Role of Systemic Lupus Erythematosus Risk Variants With Opposing Functional Effects as a Driver of Hypomorphic Expression of TNIP1 and Other Genes Within a Three-Dimensional Chromatin Network

具有相反功能效应的系统性红斑狼疮风险变异作为 TNIP1 和三维染色质网络内其他基因亚等位基因表达的驱动因素的作用

Satish Pasula, Kandice L Tessneer, Yao Fu, Jaanam Gopalakrishnan, Richard C Pelikan, Jennifer A Kelly, Graham B Wiley, Mandi M Wiley, Patrick M Gaffney

Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks

增强子组蛋白 QTL 在自身免疫风险单倍型上富集,并影响染色质网络内的基因表达

Richard C Pelikan, Jennifer A Kelly, Yao Fu, Caleb A Lareau, Kandice L Tessneer, Graham B Wiley, Mandi M Wiley, Stuart B Glenn, John B Harley, Joel M Guthridge, Judith A James, Martin J Aryee, Courtney Montgomery, Patrick M Gaffney

Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity

调节性多态性调节 HLA II 类分子的表达并促进自身免疫

Prithvi Raj, Ekta Rai, Ran Song, Shaheen Khan, Benjamin E Wakeland, Kasthuribai Viswanathan, Carlos Arana, Chaoying Liang, Bo Zhang, Igor Dozmorov, Ferdicia Carr-Johnson, Mitja Mitrovic, Graham B Wiley, Jennifer A Kelly, Bernard R Lauwerys, Nancy J Olsen, Chris Cotsapas, Christine K Garcia, Carol A

Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription

两种功能性狼疮相关 BLK 启动子变体控制细胞类型和发育阶段特异性转录

Joel M Guthridge, Rufei Lu, Harry Sun, Celi Sun, Graham B Wiley, Nicolas Dominguez, Susan R Macwana, Christopher J Lessard, Xana Kim-Howard, Beth L Cobb, Kenneth M Kaufman, Jennifer A Kelly, Carl D Langefeld, Adam J Adler, Isaac T W Harley, Joan T Merrill, Gary S Gilkeson, Diane L Kamen, Timothy B N

Genome-wide DNA methylation maps in follicular lymphoma cells determined by methylation-enriched bisulfite sequencing

通过甲基化富集亚硫酸氢盐测序确定滤泡性淋巴瘤细胞的全基因组 DNA 甲基化图谱

Jeong-Hyeon Choi, Yajun Li, Juyuan Guo, Lirong Pei, Tibor A Rauch, Robin S Kramer, Simone L Macmil, Graham B Wiley, Lynda B Bennett, Jennifer L Schnabel, Kristen H Taylor, Sun Kim, Dong Xu, Arun Sreekumar, Gerd P Pfeifer, Bruce A Roe, Charles W Caldwell, Kapil N Bhalla, Huidong Shi