Graichen Luise相关文献与解析，生知库 | 链接生命科学的每一步

Neutralizing activity against bovine H5N1 HPAIV (clade 2.3.4.4b) in human plasma after seasonal influenza vaccination

季节性流感疫苗接种后，人血浆中针对牛源H5N1高致病性禽流感病毒（2.3.4.4b分支）的中和活性

doi:10.1080/22221751.2025.2528539

Zhang, Lu; Behrens, Georg M N; Kempf, Amy; Nehlmeier, Inga; Gärtner, Sabine; Moldenhauer, Anna-Sophie; Graichen, Luise; Happle, Christine; Winkler, Michael; Dopfer-Jablonka, Alexandra; Pöhlmann, Stefan; Hoffmann, Markus

Host cell lectins ASGR1 and DC-SIGN jointly with TMEM106B confer ACE2 independence and imdevimab resistance to SARS-CoV-2 pseudovirus with spike mutation E484D.

宿主细胞凝集素 ASGR1 和 DC-SIGN 与 TMEM106B 共同赋予 ACE2 非依赖性和对刺突蛋白突变 E484D 的 SARS-CoV-2 假病毒 imdevimab 的抗性

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/jvi.01230-24

Arora Prerna, Zhang Lu, Nehlmeier Inga, Kempf Amy, Graichen Luise, Kreitz Eike, Sidarovich Anzhalika, Rocha Cheila, GÃ¤rtner Sabine, Winkler Michael, Schulz Sebastian, JÃ¤ck Hans-Martin, Hoffmann Markus, PÃ¶hlmann Stefan

Amino acid residues 655 and 969 in the spike protein of Omicron subvariant BA.1 control use of TMPRSS2 versus Cathepsin L dependent entry pathways and cell tropism

Omicron 亚变种 BA.1 的刺突蛋白中的氨基酸残基 655 和 969 控制着 TMPRSS2 与组织蛋白酶 L 依赖性入侵途径的使用以及细胞趋向性。

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0328879

Rocha, Cheila; Arora, Prerna; Zhang, Lu; Sidarovich, Anzhalika; Graichen, Luise; Moldenhauer, Anna-Sophie; Pöhlmann, Stefan; Hoffmann, Markus

细胞生物学

发表日期：2025

文献求助收藏

SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency.

SARS-CoV-2 BA.2.86 能进入肺细胞并高效逃避中和抗体

期刊:Cell

影响因子:42.5

doi:10.1016/j.cell.2023.12.025

Zhang Lu, Kempf Amy, Nehlmeier Inga, Cossmann Anne, Richter Anja, Bdeir Najat, Graichen Luise, Moldenhauer Anna-Sophie, Dopfer-Jablonka Alexandra, Stankov Metodi V, Simon-Loriere Etienne, Schulz Sebastian R, JÃ¤ck Hans-Martin, ÄiÄin-Å ain Luka, Behrens Georg M N, Drosten Christian, Hoffmann Markus, PÃ¶hlmann Stefan

细胞生物学

发表日期：2024

文献求助收藏

ACE2-independent sarbecovirus cell entry can be supported by TMPRSS2-related enzymes and can reduce sensitivity to antibody-mediated neutralization.

不依赖 ACE2 的沙贝病毒细胞进入可由 TMPRSS2 相关酶支持，并可降低对抗体介导的中和作用的敏感性

期刊:PLoS Pathogens

影响因子:4.9

doi:10.1371/journal.ppat.1012653

Zhang Lu, Cheng Hsiu-Hsin, KrÃ¼ger Nadine, HÃ¶rnich Bojan, Graichen Luise, Hahn Alexander S, Schulz Sebastian R, JÃ¤ck Hans-Martin, Stankov Metodi V, Behrens Georg M N, MÃ¼ller Marcel A, Drosten Christian, MÃ¶rer Onnen, Winkler Martin Sebastian, Qian ZhaoHui, PÃ¶hlmann Stefan, Hoffmann Markus

Acquisition of a multibasic cleavage site does not increase MERS-CoV entry into Calu-3 human lung cells

获得多碱基切割位点并不会增加MERS-CoV进入Calu-3人肺细胞的能力。

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/jvi.01305-24

Hoffmann, Markus; Kleine-Weber, Hannah; Graichen, Luise; Nehlmeier, Inga; Kempf, Amy; Moldenhauer, Anna-Sophie; Braun, Elisabeth; Assiri, Abdullah M; Kirchhoff, Frank; Sauter, Daniel; Alkharsah, Khaled R; Pöhlmann, Stefan

细胞生物学

发表日期：2024

文献求助收藏

Virological Traits of the SARS-CoV-2 BA.2.87.1 Lineage

SARS-CoV-2 BA.2.87.1谱系的病毒学特征

期刊:Vaccines

影响因子:3.4

doi:10.3390/vaccines12050487

Zhang, Lu; Dopfer-Jablonka, Alexandra; Nehlmeier, Inga; Kempf, Amy; Graichen, Luise; Calderón Hampel, Noemí; Cossmann, Anne; Stankov, Metodi V; Morillas Ramos, Gema; Schulz, Sebastian R; Jäck, Hans-Martin; Behrens, Georg M N; Pöhlmann, Stefan; Hoffmann, Markus

Entorhinal grid-like codes and time-locked network dynamics track others navigating through space

内嗅皮层网格状编码和时间锁定的网络动力学追踪其他在空间中导航的个体。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-023-35819-3

Wagner, Isabella C; Graichen, Luise P; Todorova, Boryana; Lüttig, Andre; Omer, David B; Stangl, Matthias; Lamm, Claus

发表日期：2023

文献求助收藏

Efficient antibody evasion but reduced ACE2 binding by the emerging SARS-CoV-2 variant B.1.640.2

新出现的SARS-CoV-2变种B.1.640.2具有高效的抗体逃避能力，但其ACE2结合能力降低。

期刊:Cellular & Molecular Immunology

影响因子:19.8

doi:10.1038/s41423-022-00870-5

Arora, Prerna; Kempf, Amy; Nehlmeier, Inga; Graichen, Luise; Schulz, Sebastian; Cossmann, Anne; Dopfer-Jablonka, Alexandra; Winkler, Martin S; Jäck, Hans-Martin; Behrens, Georg M N; Pöhlmann, Stefan; Hoffmann, Markus

Entorhinal grid-like codes for visual space during memory formation

记忆形成过程中内嗅皮层对视觉空间的网格状编码

Neutralizing activity against bovine H5N1 HPAIV (clade 2.3.4.4b) in human plasma after seasonal influenza vaccination

季节性流感疫苗接种后，人血浆中针对牛源H5N1高致病性禽流感病毒（2.3.4.4b分支）的中和活性

Host cell lectins ASGR1 and DC-SIGN jointly with TMEM106B confer ACE2 independence and imdevimab resistance to SARS-CoV-2 pseudovirus with spike mutation E484D.

宿主细胞凝集素 ASGR1 和 DC-SIGN 与 TMEM106B 共同赋予 ACE2 非依赖性和对刺突蛋白突变 E484D 的 SARS-CoV-2 假病毒 imdevimab 的抗性

Amino acid residues 655 and 969 in the spike protein of Omicron subvariant BA.1 control use of TMPRSS2 versus Cathepsin L dependent entry pathways and cell tropism

Omicron 亚变种 BA.1 的刺突蛋白中的氨基酸残基 655 和 969 控制着 TMPRSS2 与组织蛋白酶 L 依赖性入侵途径的使用以及细胞趋向性。

SARS-CoV-2 BA.2.86 enters lung cells and evades neutralizing antibodies with high efficiency.

SARS-CoV-2 BA.2.86 能进入肺细胞并高效逃避中和抗体

ACE2-independent sarbecovirus cell entry can be supported by TMPRSS2-related enzymes and can reduce sensitivity to antibody-mediated neutralization.

不依赖 ACE2 的沙贝病毒细胞进入可由 TMPRSS2 相关酶支持，并可降低对抗体介导的中和作用的敏感性

Acquisition of a multibasic cleavage site does not increase MERS-CoV entry into Calu-3 human lung cells

获得多碱基切割位点并不会增加MERS-CoV进入Calu-3人肺细胞的能力。

Virological Traits of the SARS-CoV-2 BA.2.87.1 Lineage

SARS-CoV-2 BA.2.87.1谱系的病毒学特征

Entorhinal grid-like codes and time-locked network dynamics track others navigating through space

内嗅皮层网格状编码和时间锁定的网络动力学追踪其他在空间中导航的个体。

Efficient antibody evasion but reduced ACE2 binding by the emerging SARS-CoV-2 variant B.1.640.2

新出现的SARS-CoV-2变种B.1.640.2具有高效的抗体逃避能力，但其ACE2结合能力降低。