Grantyn相关文献与解析，生知库 | 链接生命科学的每一步

Brandt, Nicola; Battefeld, Arne; Suckau, Olga; Stadler, Konstantin; Singh, Bhumika; Zhang, Pei; Aoki, Junken; Chun, Jerold; Henneberger, Christian; Grantyn, Rosemarie; Vogt, Johannes; Nitsch, Robert; Strauss, Ulf; Bräuer, Anja U

神经科学

发表日期：2025

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Uncoupling the Excitatory Amino Acid Transporter 2 From Its C-Terminal Interactome Restores Synaptic Glutamate Clearance at Corticostriatal Synapses and Alleviates Mutant Huntingtin-Induced Hypokinesia

将兴奋性氨基酸转运体 2 与其 C 端相互作用组分离可恢复皮质纹状体突触处的突触谷氨酸清除，并缓解突变型亨廷顿蛋白引起的运动减少

期刊:Frontiers in Cellular Neuroscience

影响因子:4.2

doi:10.3389/fncel.2021.792652

Stefan Hirschberg, Anton Dvorzhak, Seyed M A Rasooli-Nejad, Svilen Angelov, Marieluise Kirchner, Philipp Mertins, Gilla Lättig-Tünnemann, Christoph Harms, Dietmar Schmitz, Rosemarie Grantyn

信号转导

发表日期：2022

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Single Synapse Indicators of Impaired Glutamate Clearance Derived from Fast iGlu u Imaging of Cortical Afferents in the Striatum of Normal and Huntington (Q175) Mice

正常和亨廷顿 (Q175) 小鼠纹状体皮质传入神经元的快速 iGlu u 成像显示谷氨酸清除受损的单突触指标

期刊:Journal of Neuroscience

影响因子:4.4

doi:10.1523/JNEUROSCI.2865-18.2019

Anton Dvorzhak, Nordine Helassa, Katalin Török, Dietmar Schmitz, Rosemarie Grantyn

神经

发表日期：2019

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Unravelling and Exploiting Astrocyte Dysfunction in Huntington's Disease

揭示并利用亨廷顿病中的星形胶质细胞功能障碍

期刊:Trends in Neurosciences

影响因子:15.1

doi:10.1016/j.tins.2017.05.002

Khakh, Baljit S; Beaumont, Vahri; Cachope, Roger; Munoz-Sanjuan, Ignacio; Goldman, Steven A; Grantyn, Rosemarie

Functional Indicators of Glutamate Transport in Single Striatal Astrocytes and the Influence of Kir4.1 in Normal and Huntington Mice

正常和亨廷顿小鼠中单个纹状体星形胶质细胞谷氨酸转运的功能指标及Kir4.1的影响

期刊:Journal of Neuroscience

影响因子:4.4

doi:10.1523/JNEUROSCI.0316-16.2016

Anton Dvorzhak, Tatyana Vagner, Knut Kirmse, Rosemarie Grantyn

Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3

由于 GAT-3 途径星形胶质细胞 GABA 释放减少，亨廷顿小鼠纹状体输出神经元的强直抑制降低

期刊:Frontiers in Neural Circuits

影响因子:3.4

doi:10.3389/fncir.2013.00188

Anna M Wójtowicz, Anton Dvorzhak, Marcus Semtner, Rosemarie Grantyn

High frequency stimulation of the subthalamic nucleus leads to presynaptic GABA(B)-dependent depression of subthalamo-nigral afferents

丘脑底核的高频刺激导致突触前GABA（B）依赖的丘脑底核-黑质传入神经元的抑制

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0082191

Anton Dvorzhak, Christoph Gertler, Daniel Harnack, Rosemarie Grantyn

神经

发表日期：2013

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Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin

强直性 mGluR5/CB1 依赖性抑制是携带突变型亨廷顿蛋白的小鼠纹状体中的病理生理标志

期刊:Journal of Physiology-London

影响因子:2.1

doi:10.1113/jphysiol.2012.241018

Anton Dvorzhak, Marcus Semtner, Donald S Faber, Rosemarie Grantyn

信号转导

发表日期：2013

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Functional hallmarks of GABAergic synapse maturation and the diverse roles of neurotrophins

GABA能突触成熟的功能特征及神经营养因子的多样化作用

期刊:Frontiers in Cellular Neuroscience

影响因子:4

doi:10.3389/fncel.2011.00013

Grantyn, Rosemarie; Henneberger, Christian; Jüttner, René; Meier, Jochen C; Kirischuk, Sergei

神经科学

发表日期：2011

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Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy

甘氨酸能强直抑制海马神经元，通过去极化 GABA 能传递，引发颞叶癫痫的组织病理学症状

期刊:Journal of Cellular and Molecular Medicine

影响因子:4.3

doi:10.1111/j.1582-4934.2008.00357.x

Sabrina A Eichler, Sergei Kirischuk, René Jüttner, Philipp K Schaefermeier, Pascal Legendre, Thomas-Nicolas Lehmann, Tengis Gloveli, Rosemarie Grantyn, Jochen C Meier

Lysophosphatidic acid selectively modulates excitatory transmission in hippocampal neurons

溶血磷脂酸选择性地调节海马神经元的兴奋性传递

Uncoupling the Excitatory Amino Acid Transporter 2 From Its C-Terminal Interactome Restores Synaptic Glutamate Clearance at Corticostriatal Synapses and Alleviates Mutant Huntingtin-Induced Hypokinesia

将兴奋性氨基酸转运体 2 与其 C 端相互作用组分离可恢复皮质纹状体突触处的突触谷氨酸清除，并缓解突变型亨廷顿蛋白引起的运动减少

Single Synapse Indicators of Impaired Glutamate Clearance Derived from Fast iGlu u Imaging of Cortical Afferents in the Striatum of Normal and Huntington (Q175) Mice

正常和亨廷顿 (Q175) 小鼠纹状体皮质传入神经元的快速 iGlu u 成像显示谷氨酸清除受损的单突触指标

Unravelling and Exploiting Astrocyte Dysfunction in Huntington's Disease

揭示并利用亨廷顿病中的星形胶质细胞功能障碍

Functional Indicators of Glutamate Transport in Single Striatal Astrocytes and the Influence of Kir4.1 in Normal and Huntington Mice

正常和亨廷顿小鼠中单个纹状体星形胶质细胞谷氨酸转运的功能指标及Kir4.1的影响

Reduced tonic inhibition in striatal output neurons from Huntington mice due to loss of astrocytic GABA release through GAT-3

由于 GAT-3 途径星形胶质细胞 GABA 释放减少，亨廷顿小鼠纹状体输出神经元的强直抑制降低

High frequency stimulation of the subthalamic nucleus leads to presynaptic GABA(B)-dependent depression of subthalamo-nigral afferents

丘脑底核的高频刺激导致突触前GABA（B）依赖的丘脑底核-黑质传入神经元的抑制

Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin

强直性 mGluR5/CB1 依赖性抑制是携带突变型亨廷顿蛋白的小鼠纹状体中的病理生理标志

Functional hallmarks of GABAergic synapse maturation and the diverse roles of neurotrophins

GABA能突触成熟的功能特征及神经营养因子的多样化作用

Glycinergic tonic inhibition of hippocampal neurons with depolarizing GABAergic transmission elicits histopathological signs of temporal lobe epilepsy

甘氨酸能强直抑制海马神经元，通过去极化 GABA 能传递，引发颞叶癫痫的组织病理学症状