日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeting Expanded CUG and CTG Repeats as a Therapeutic Approach for Myotonic Dystrophy Type 1 (DM1)

以扩增的 CUG 和 CTG 重复序列为靶点治疗 1 型强直性肌营养不良症 (DM1)

Richagneux, Camille; Granzhan, Anton

Conformational Change in a Four-Tetrad DNA G-Quadruplex upon Intercalation of a Small-Molecule Ligand PyDH2

小分子配体 PyDH2 插入四联体 DNA G-四链体后发生的构象变化

Martin, Kailey N; Lam, Gwendolyn; Reznichenko, Oksana; Brunner, Kyle E; Zdilla, Michael J; McCarthy, Sawyer E; Granzhan, Anton; Yatsunyk, Liliya A

The Epstein-Barr virus EBNA1 protein binds to G-quadruplexes in its own mRNA hence controlling its expression and immune evasion of the virus.

爱泼斯坦-巴尔病毒 EBNA1 蛋白与其自身 mRNA 中的 G-四链体结合,从而控制其表达和病毒的免疫逃避

Dinh Van-Trang, Loaëc Nadège, Quillévéré Alicia, Keruzoré Marc, Peynet Aline, Le Sénéchal Ronan, Teulade-Fichou Marie-Paule, Corcos Laurent, Martins Rodrigo Prado, Granzhan Anton, Blondel Marc

Unprecedented reactivity of polyamines with aldehydic DNA modifications: structural determinants of reactivity, characterization and enzymatic stability of adducts

多胺与醛基DNA修饰的空前反应性:反应性的结构决定因素、加合物的表征和酶稳定性

Gusti Ngurah Putu, Eka Putra; Cattiaux, Laurent; Lavergne, Thomas; Pommier, Yves; Bombard, Sophie; Granzhan, Anton

Novel Synthesis of IMC-48 and Affinity Evaluation with Different i-Motif DNA Sequences

IMC-48 的新型合成及其与不同 i-Motif DNA 序列的亲和力评价

Berthiol, Florian; Boissieras, Joseph; Bonnet, Hugues; Pierrot, Marie; Philouze, Christian; Poisson, Jean-François; Granzhan, Anton; Dejeu, Jérôme; Defrancq, Eric

Dual targeting of higher-order DNA structures by azacryptands induces DNA junction-mediated DNA damage in cancer cells

氮杂隐窝化合物对高级DNA结构的双重靶向作用可诱导癌细胞中DNA连接介导的DNA损伤。

Zell, Joanna; Duskova, Katerina; Chouh, Leïla; Bossaert, Madeleine; Chéron, Nicolas; Granzhan, Anton; Britton, Sébastien; Monchaud, David

Sneaking Out for Happy Hour: Yeast-Based Approaches to Explore and Modulate Immune Response and Immune Evasion

偷偷溜出去享受欢乐时光:利用酵母探索和调节免疫反应和免疫逃逸

Angrand, Gaëlle; Quillévéré, Alicia; Loaëc, Nadège; Daskalogianni, Chrysoula; Granzhan, Anton; Teulade-Fichou, Marie-Paule; Fahraeus, Robin; Prado Martins, Rodrigo; Blondel, Marc

TWJ-Screen: an isothermal screening assay to assess ligand/DNA junction interactions in vitro

TWJ-Screen:一种体外评估配体/DNA连接相互作用的等温筛选方法

Guyon, Ludivine; Pirrotta, Marc; Duskova, Katerina; Granzhan, Anton; Teulade-Fichou, Marie-Paule; Monchaud, David

Probing of G-Quadruplex Structures via Ligand-Sensitized Photochemical Reactions in (Br)U-Substituted DNA

利用配体敏化光化学反应探测(Br)U取代DNA中的G-四链体结构

Saha, Abhijit; Bombard, Sophie; Granzhan, Anton; Teulade-Fichou, Marie-Paule