日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Assessment of chemical modifications of sites in the CDRs of recombinant antibodies: Susceptibility vs. functionality of critical quality attributes

重组抗体 CDR 位点化学修饰评估:关键质量属性的敏感性与功能性

Markus Haberger, Katrin Bomans, Katharina Diepold, Michaela Hook, Jana Gassner, Tilman Schlothauer, Adrian Zwick, Christian Spick, Jochen Felix Kepert, Brigitte Hienz, Michael Wiedmann, Hermann Beck, Philipp Metzger, Michael Mølhøj, Constanze Knoblich, Ulla Grauschopf, Dietmar Reusch, Patrick Bulau

Cytotoxin ClyA from Escherichia coli assembles to a 13-meric pore independent of its redox-state

来自大肠杆菌的细胞毒素ClyA组装成一个13聚体孔道,该组装过程与其氧化还原状态无关。

Eifler, Nora; Vetsch, Michael; Gregorini, Marco; Ringler, Philippe; Chami, Mohamed; Philippsen, Ansgar; Fritz, Andrea; Müller, Shirley A; Glockshuber, Rudi; Engel, Andreas; Grauschopf, Ulla