日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A HIV-Tat/C4-binding protein chimera encoded by a DNA vaccine is highly immunogenic and contains acute EcoHIV infection in mice

一种由DNA疫苗编码的HIV-Tat/C4结合蛋白嵌合体具有高度免疫原性,并可在小鼠中诱发急性EcoHIV感染。

Tomusange, Khamis; Wijesundara, Danushka; Gummow, Jason; Garrod, Tamsin; Li, Yanrui; Gray, Lachlan; Churchill, Melissa; Grubor-Bauk, Branka; Gowans, Eric J

Reliable genotypic tropism tests for the major HIV-1 subtypes

针对主要 HIV-1 亚型的可靠基因型嗜性检测

Cashin, Kieran; Gray, Lachlan R; Harvey, Katherine L; Perez-Bercoff, Danielle; Lee, Guinevere Q; Sterjovski, Jasminka; Roche, Michael; Demarest, James F; Drummond, Fraser; Harrigan, P Richard; Churchill, Melissa J; Gorry, Paul R

HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research

HIV-1在中枢神经系统中的转录调控及其对HIV治愈研究的意义

Churchill, Melissa J; Cowley, Daniel J; Wesselingh, Steve L; Gorry, Paul R; Gray, Lachlan R

HIV-1 entry and trans-infection of astrocytes involves CD81 vesicles

HIV-1进入星形胶质细胞并进行跨细胞感染涉及CD81囊泡

Gray, Lachlan R; Turville, Stuart G; Hitchen, Tina L; Cheng, Wan-Jung; Ellett, Anne M; Salimi, Hamid; Roche, Michael J; Wesselingh, Steve L; Gorry, Paul R; Churchill, Melissa J

A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations

尽管耐药水平存在差异且缺乏常见的gp120耐药突变,但临床上HIV-1对CCR5拮抗剂马拉维罗克产生耐药性的常见机制

Roche, Michael; Salimi, Hamid; Duncan, Renee; Wilkinson, Brendan L; Chikere, Kelechi; Moore, Miranda S; Webb, Nicholas E; Zappi, Helena; Sterjovski, Jasminka; Flynn, Jacqueline K; Ellett, Anne; Gray, Lachlan R; Lee, Benhur; Jubb, Becky; Westby, Mike; Ramsland, Paul A; Lewin, Sharon R; Payne, Richard J; Churchill, Melissa J; Gorry, Paul R

CoRSeqV3-C: a novel HIV-1 subtype C specific V3 sequence based coreceptor usage prediction algorithm

CoRSeqV3-C:一种新型的基于HIV-1 C亚型特异性V3序列的辅助受体使用预测算法

Cashin, Kieran; Gray, Lachlan R; Jakobsen, Martin R; Sterjovski, Jasminka; Churchill, Melissa J; Gorry, Paul R

Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection

对一组未接受抗逆转录病毒治疗且HIV-1 C亚型感染进展的患者进行CCR5和CXCR4使用情况的纵向分析

Jakobsen, Martin R; Cashin, Kieran; Roche, Michael; Sterjovski, Jasminka; Ellett, Anne; Borm, Katharina; Flynn, Jacqueline; Erikstrup, Christian; Gouillou, Maelenn; Gray, Lachlan R; Saksena, Nitin K; Wang, Bin; Purcell, Damian F J; Kallestrup, Per; Zinyama-Gutsire, Rutendo; Gomo, Exnevia; Ullum, Henrik; Ostergaard, Lars; Lee, Benhur; Ramsland, Paul A; Churchill, Melissa J; Gorry, Paul R

The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes

核苷类逆转录酶抑制剂拉米夫定、司他夫定和齐多夫定降低了星形胶质细胞中HIV-1的抑制活性。

Gray, Lachlan R; Tachedjian, Gilda; Ellett, Anne M; Roche, Michael J; Cheng, Wan-Jung; Guillemin, Gilles J; Brew, Bruce J; Turville, Stuart G; Wesselingh, Steve L; Gorry, Paul R; Churchill, Melissa J

Reduced basal transcriptional activity of central nervous system-derived HIV type 1 long terminal repeats

中枢神经系统来源的 HIV 1 型长末端重复序列的基础转录活性降低

Gray, Lachlan R; Cowley, Daniel; Crespan, Emma; Welsh, Casey; Mackenzie, Charlene; Wesselingh, Steve L; Gorry, Paul R; Churchill, Melissa J

HIV infection of dendritic cells subverts the IFN induction pathway via IRF-1 and inhibits type 1 IFN production.

HIV 感染树突状细胞会通过 IRF-1 破坏 IFN 诱导途径,抑制 1 型 IFN 的产生

Harman Andrew N, Lai Joey, Turville Stuart, Samarajiwa Shamith, Gray Lachlan, Marsden Valerie, Mercier Sarah K, Jones Kate, Nasr Najla, Rustagi Arjun, Cumming Helen, Donaghy Heather, Mak Johnson, Gale Michael Jr, Churchill Melissa, Hertzog Paul, Cunningham Anthony L