日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Probing the Interactions of Thiazole Abietane Inhibitors with the Human Serine Hydrolases ABHD16A and ABHD12

探究噻唑类阿比坦抑制剂与人丝氨酸水解酶ABHD16A和ABHD12的相互作用

Ahonen, Tiina J; Ng, Choa P; Farinha, Beatriz; Almeida, Bárbara; Victor, Bruno L; Reynolds, Christopher; Kalso, Eija; Yli-Kauhaluoma, Jari; Greaves, Jennifer; Moreira, Vânia M

The Hydrophobic Cysteine-rich Domain of SNAP25 Couples with Downstream Residues to Mediate Membrane Interactions and Recognition by DHHC Palmitoyl Transferases

SNAP25 的疏水性富含半胱氨酸结构域与下游残基结合,介导膜相互作用和 DHHC 棕榈酰转移酶的识别。

Greaves, Jennifer; Prescott, Gerald R; Fukata, Yuko; Fukata, Masaki; Salaun, Christine; Chamberlain, Luke H

The linker domain of the SNARE protein SNAP25 acts as a flexible molecular spacer that ensures efficient S-acylation.

SNARE 蛋白 SNAP25 的连接域作为灵活的分子间隔物,确保高效的 S-酰化

Salaun Christine, Greaves Jennifer, Tomkinson Nicholas C O, Chamberlain Luke H

Tracking intracellular uptake and localisation of alkyne tagged fatty acids using Raman spectroscopy

利用拉曼光谱追踪炔基标记脂肪酸的细胞内摄取和定位

Jamieson, Lauren E; Greaves, Jennifer; McLellan, Jayde A; Munro, Kevin R; Tomkinson, Nicholas C O; Chamberlain, Luke H; Faulds, Karen; Graham, Duncan

Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry.

通过点击化学揭示了zDHHC家族S-酰基转移酶脂肪酸选择性的分子基础

Greaves Jennifer, Munro Kevin R, Davidson Stuart C, Riviere Matthieu, Wojno Justyna, Smith Terry K, Tomkinson Nicholas C O, Chamberlain Luke H

The C-terminal domain of zDHHC2 contains distinct sorting signals that regulate intracellular localisation in neurons and neuroendocrine cells

zDHHC2 的 C 端结构域包含不同的分选信号,这些信号调控其在神经元和神经内分泌细胞中的细胞内定位。

Salaun, Christine; Ritchie, Louise; Greaves, Jennifer; Bushell, Trevor J; Chamberlain, Luke H

Endoplasmic reticulum localization of DHHC palmitoyltransferases mediated by lysine-based sorting signals

赖氨酸分选信号介导的DHHC棕榈酰转移酶的内质网定位

Gorleku, Oforiwa A; Barns, Anna-Marie; Prescott, Gerald R; Greaves, Jennifer; Chamberlain, Luke H

Differential palmitoylation regulates intracellular patterning of SNAP25

差异棕榈酰化调控SNAP25的细胞内模式

Greaves, Jennifer; Chamberlain, Luke H

The palmitoyl transferase DHHC2 targets a dynamic membrane cycling pathway: regulation by a C-terminal domain

棕榈酰转移酶DHHC2靶向动态膜循环通路:受C端结构域调控

Greaves, Jennifer; Carmichael, Juliet A; Chamberlain, Luke H

The hydrophobic cysteine-rich domain of SNAP25 couples with downstream residues to mediate membrane interactions and recognition by DHHC palmitoyl transferases

SNAP25 的疏水性富含半胱氨酸的结构域与下游残基结合,介导膜相互作用以及 DHHC 棕榈酰转移酶的识别。

Greaves, Jennifer; Prescott, Gerald R; Fukata, Yuko; Fukata, Masaki; Salaun, Christine; Chamberlain, Luke H