Novel PD-1-targeted, activity-optimized IL-15 mutein SOT201 acting in cis provides antitumor activity superior to PD1-IL2v.
新型 PD-1 靶向、活性优化的 IL-15 突变体 SOT201 以顺式作用提供优于 PD1-IL2v 的抗肿瘤活性
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-010736
Matuskova Hana, Marasek Pavel, Mazhara Vladyslav, Simonova Ekaterina, Kosinova Lucie, Danek Petr, Danova Klara, Sajnerova Katerina, Malatova Iva, Hrabankova Klara, Greco Denise, Martinec Ondrej, Fabisik Matej, Podzimkova Nada, Hladikova Kamila, Behalova Katerina, Antosova Zuzana, Sirova Milada, Mikyskova Romana, Reinis Milan, Kovar Marek, Béchard David, Moebius Ulrich, Palova Jelinkova Lenka, Spisek Radek, Steegmaier Martin, Adkins Irena
