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日期影响因子

Intranasal immunization with live-attenuated RSV-vectored SARS-CoV-2 vaccines elicits antigen-specific systemic and mucosal immunity and protects against viral challenge and natural infection

鼻内接种减毒活病毒载体SARS-CoV-2疫苗可诱导抗原特异性全身和黏膜免疫，并能抵抗病毒攻击和自然感染。

doi:10.64898/2026.03.30.715311

Botta, Davide; Schultz, Michael D; Silva-Sanchez, Aaron; Kalange, Davies; Akther, Jobaida; Zhou, Fen; Tipper, Jennifer L; Yang, Guang; Schaefers, Levi T; Barkley, Courtney A; Qiu, Shihong; Foote, Jeremy B; Tioni, Mariana F; Weiss, Christopher M; Phan, Shannon I; Green, Todd J; Leal, Sixto M Jr; Harrod, Kevin S; King, Rodney G; Moore, Martin L; Randall, Troy D; Tang, Roderick S; Lund, Frances E

免疫/内分泌

发表日期：2026

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Identification of a potent V3 glycan site broadly neutralizing antibody targeting an N332(gp120) glycan-independent epitope

鉴定出一种针对N332(gp120)糖基非依赖性表位的强效V3糖基位点广谱中和抗体

期刊:Nature Immunology

doi:10.1038/s41590-025-02385-3

Gieselmann, Lutz; DeLaitsch, Andrew T; Rohde, Malena; Radford, Caelan; Worczinski, Johanna; Ashurov, Anna; Ahmadov, Elvin; Burger, Judith A; Havenar-Daughton, Colin; Deshpande, Sharvari; Giovannoni, Federico; Corti, Davide; Kreer, Christoph; Ercanoglu, Meryem Seda; Schommers, Philipp; Georgiev, Ivelin S; West, Anthony P Jr; Knüfer, Jacqueline; Stumpf, Ricarda; Kroidl, Arne; Geldmacher, Christof; Maganga, Lucas; William, Wiston; Ntinginya, Nyanda E; Hoelscher, Michael; Yang, Zhengrong; Wei, Qing; Renfrow, Matthew B; Green, Todd J; Novak, Jan; van Gils, Marit J; Gristick, Harry B; Gruell, Henning; Bloom, Jesse D; Seaman, Michael S; Bjorkman, Pamela J; Klein, Florian

发表日期：2026

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Topography of the HLA-A protein enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients

HLA-A蛋白的拓扑结构决定了移植受者体内共享且趋同的免疫优势B细胞和抗体同种异体反应。

期刊:Immunity

影响因子:26.3

doi:10.1016/j.immuni.2025.10.014

Killian, John T Jr; King, R Glenn; Lucander, Aaron C K; Kizziah, James L; Fucile, Christopher F; Diaz-Avalos, Ruben; Qiu, Shihong; Silva-Sanchez, Aaron; Mousseau, Betty J; Macon, Kevin J; Callahan, Amanda R; Yang, Guang; Hossain, M Emon; Akther, Jobaida; Good, Daryl B; Kelso, Susan; Houp, Julie A; Rosenblum, Frida; Porrett, Paige M; Ong, Song C; Kumar, Vineeta; Saphire, Erica Ollmann; Kearney, John F; Randall, Troy D; Rosenberg, Alexander F; Green, Todd J; Lund, Frances E

细胞生物学

免疫/内分泌

发表日期：2025

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Identification of a broad and potent V3 glycan site bNAb targeting an N332(gp120) glycan-independent epitope

鉴定出一种靶向N332(gp120)糖基非依赖性表位的广谱高效V3糖基化位点bNAb

doi:10.1101/2025.09.05.674437

Gieselmann, Lutz; DeLaitsch, Andrew T; Rohde, Malena; Radford, Caelan; Worczinski, Johanna; Momot, Anna; Ahmadov, Elvin; Burger, Judith A; Havenar-Daughton, Colin; Deshpande, Sharvari; Giovannoni, Federico; Corti, Davide; Kreer, Christoph; Ercanoglu, Meryem Seda; Schommers, Philipp; Georgiev, Ivelin S; West, Anthony P Jr; Knüfer, Jacqueline; Stumpf, Ricarda; Kroidl, Arne; Geldmacher, Christof; Maganga, Lucas; William, Wiston; Ntinginya, Nyanda E; Hoelscher, Michael; Yang, Zhengrong; Wei, Qing; Renfrow, Matthew; Green, Todd J; Novak, Jan; van Gils, Marit J; Gristick, Harry B; Gruell, Henning; Bloom, Jesse D; Seaman, Michael S; Bjorkman, Pamela J; Klein, Florian

发表日期：2025

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The Type 1 Diabetes-Associated Single Nucleotide Polymorphism rs1990760 in IFIH1 Is Associated with Increased Basal Type I IFNs and IFN-stimulated Gene Expression

1 型糖尿病相关单核苷酸多态性 rs1990760（位于 IFIH1 基因）与基础 I 型干扰素水平升高和干扰素刺激基因表达增强相关。

期刊:Journal of Immunology

影响因子:3.4

doi:10.4049/jimmunol.2400344

Taylor, Jared P; Blum, Samuel I; Graffeo, Hollis C; Shang, Qiao; Qiu, Shihong; Green, Todd J; Botta, Davide; Lund, Frances E; Tse, Hubert M

发表日期：2024

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O-glycosylation of IgA1 and the pathogenesis of an autoimmune disease IgA nephropathy

IgA1的O-糖基化及其与自身免疫性疾病IgA肾病的发病机制的关系

期刊:Glycobiology

影响因子:3.3

doi:10.1093/glycob/cwae060

Novak, Jan; King, R Glenn; Yother, Janet; Renfrow, Matthew B; Green, Todd J

自身免疫性疾病

免疫/内分泌

发表日期：2024

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Potent neutralization by a receptor binding domain monoclonal antibody with broad specificity for SARS-CoV-2 JN.1 and other variants

一种对SARS-CoV-2 JN.1及其他变种具有广泛特异性的受体结合域单克隆抗体，可有效中和病毒。

doi:10.1101/2024.04.27.591446

Piepenbrink, Michael S; Khalil, Ahmed Magdy; Chang, Ana; Mostafa, Ahmed; Basu, Madhubanti; Sarkar, Sanghita; Panjwani, Simran; Ha, Yaelyn H; Ma, Yao; Ye, Chengjin; Wang, Qian; Green, Todd J; Kizziah, James L; Erdmann, Nathaniel B; Goepfert, Paul A; Liu, Lihong; Ho, David D; Martinez-Sobrido, Luis; Walter, Mark R; Kobie, James J

单克隆抗体

发表日期：2024

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Emerging Biochemical and Immunologic Mechanisms in the Pathogenesis of IgA Nephropathy

IgA肾病发病机制中新出现的生化和免疫学机制

doi:10.1016/j.semnephrol.2025.151565

Novak, Jan; Reily, Colin; Steers, Nicholas J; Schumann, Tillie; Rizk, Dana V; Julian, Bruce A; Kiryluk, Krzysztof; Gharavi, Ali G; Green, Todd J

免疫/内分泌

发表日期：2024

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HLA topography enforces shared and convergent immunodominant B cell and antibody alloresponses in transplant recipients

HLA拓扑结构决定了移植受者体内共享且趋同的免疫优势B细胞和抗体同种异体反应。

doi:10.1101/2023.03.31.534734

Killian, John T; Glenn King, R; Lucander, Aaron C K; Kizziah, James L; Fucile, Christopher F; Diaz-Avalos, Ruben; Qiu, Shihong; Silva-Sanchez, Aaron; Mousseau, Betty J; Macon, Kevin J; Callahan, Amanda R; Yang, Guang; Emon Hossain, M; Akther, Jobaida; Good, Daryl B; Kelso, Susan; Houp, Julie A; Rosenblum, Frida; Porrett, Paige M; Ong, Song C; Kumar, Vineeta; Saphire, Erica Ollmann; Kearney, John F; Randall, Troy D; Rosenberg, Alexander F; Green, Todd J; Lund, Frances E

细胞生物学

免疫/内分泌

发表日期：2024

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Author Correction: Protein-based profiling of the human IgA1 clonal repertoire revealed shared clones of serum polymeric IgA1 and milk secretory IgA1

作者更正：基于蛋白质的人类 IgA1 克隆库分析揭示了血清多聚 IgA1 和乳汁分泌型 IgA1 的共有克隆

期刊:Cellular & Molecular Immunology

影响因子:19.8

doi:10.1038/s41423-023-00977-3

Novak, Jan; Renfrow, Matthew B; King, R Glenn; Reily, Colin; Green, Todd J

发表日期：2023

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