日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis

丙酮酸代谢决定了纤维形成过程中成纤维细胞对 GLS1 抑制的敏感性

Greg Contento, Jo-Anne Am Wilson, Brintha Selvarajah, Manuela Platé, Delphine Guillotin, Valle Morales, Marcello Trevisani, Vanessa Pitozzi, Katiuscia Bianchi, Rachel C Chambers

mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1-induced collagen biosynthesis

mTORC1 扩增 ATF4 依赖的从头丝氨酸-甘氨酸途径,在 TGF-β1 诱导的胶原生物合成过程中提供甘氨酸

Brintha Selvarajah, Ilan Azuelos, Manuela Platé, Delphine Guillotin, Ellen J Forty, Greg Contento, Hannah V Woodcock, Matthew Redding, Adam Taylor, Gino Brunori, Pascal F Durrenberger, Riccardo Ronzoni, Andy D Blanchard, Paul F Mercer, Dimitrios Anastasiou, Rachel C Chambers