FASN inhibition targets multiple drivers of NASH by reducing steatosis, inflammation and fibrosis in preclinical models
FASN 抑制可通过减少临床前模型中的脂肪变性、炎症和纤维化来靶向 NASH 的多种驱动因素
期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-022-19459-z
Marie O'Farrell, Greg Duke, Richard Crowley, Douglas Buckley, Eduardo B Martins, Dipankar Bhattacharya, Scott L Friedman, George Kemble