日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Astrocytes and Alcohol Throughout the Lifespan

星形胶质细胞与酒精在整个生命周期中的关系

Guizzetti, Marina; Mangieri, Regina A; Ezerskiy, Lubov A; Hashimoto, Joel G; Bajo, Michal; Farris, Sean P; Homanics, Gregg E; Lasek, Amy W; Mayfield, R Dayne; Messing, Robert O; Roberto, Marisa

An increased copy number of glycine decarboxylase (GLDC) associated with psychosis reduces extracellular glycine and impairs NMDA receptor function

精神病患者体内甘氨酸脱羧酶 (GLDC) 拷贝数增加,导致细胞外甘氨酸水平降低,并损害 NMDA 受体功能。

Kambali, Maltesh; Li, Yan; Unichenko, Petr; Feria Pliego, Jessica A; Yadav, Rachita; Liu, Jing; McGuinness, Patrick; Cobb, Johanna G; Wang, Muxiao; Nagarajan, Rajasekar; Lyu, Jinrui; Vongsouthi, Vanessa; Jackson, Colin J; Engin, Elif; Coyle, Joseph T; Shin, Jaeweon; Hodgson, Nathaniel W; Hensch, Takao K; Talkowski, Michael E; Homanics, Gregg E; Bolshakov, Vadim Y; Henneberger, Christian; Rudolph, Uwe

Decreased cigarette smoking may partially explain the increased prevalence of antinuclear antibodies in the United States

美国吸烟人数的减少或许可以部分解释抗核抗体患病率上升的原因。

Dinse, Gregg E; Weinberg, Clarice R; Parks, Christine G; Co, Caroll A; Priest, Jessica T; Chan, Edward K L; Miller, Frederick W

Lessons learned from evaluating defined chemical mixtures in a high-throughput estrogen receptor assay system

从高通量雌激素受体检测系统中评估特定化学混合物所汲取的经验教训

Parham, Fred; Eccles, Kristin M; Rider, Cynthia V; Sakamuru, Srilatha; Xia, Menghang; Huang, Ruili; Tice, Raymond R; Dinse, Gregg E; DeVito, Michael J

Newly Identified TPI Deficiency Treatments Function for Novel Disease-Causing Allele, TPI1(R5G).

新发现的 TPI 缺乏症治疗方法针对新的致病等位基因 TPI1(R5G)。

Figura Joseph R, Roberts Presley, Sawka Riley, Chambers Maci, Claudio Marcelo, Vollmer Laura L, Vogt Andreas, Homanics Gregg E, van Beers Eduard, Donge Mylene, Scalais Emmanuel, Sorlin Arthur, Jou Ariana J, VanDemark Andrew P, Palladino Michael J

Discovery and validation of small molecule stabilizers of mutant triose phosphate isomerase (TPI) as potential lead candidates for TPI deficiency

发现并验证突变型磷酸丙糖异构酶 (TPI) 小分子稳定剂作为 TPI 缺乏症的潜在先导化合物

Vollmer, Laura L; Roberts, Presley; Eicher, Samantha L; Wołosowicz, Marta; Patel, Priyal; Figura, Joseph R; Donahue, Ella R; Berkowitz, Josh; Gavlock, Dillon; Wipf, Peter; LaPorte, Matt; Mullett, Steven J; Shillington, Amelle; Homanics, Gregg E; Palladino, Michael J; Vogt, Andreas

Early molecular events of autosomal-dominant Alzheimer's disease in marmosets with PSEN1 mutations

携带 PSEN1 突变的狨猴常染色体显性阿尔茨海默病的早期分子事件

Gregg E Homanics, Jung Eun Park, Lauren Bailey, David J Schaeffer, Lauren Schaeffer, Jie He, Shuoran Li, Tingting Zhang, Annat Haber, Catrina Spruce, Anna Greenwood, Takeshi Murai, Laura Schultz, Lauren Mongeau, Seung-Kwon Ha, Julia Oluoch, Brianne Stein, Sang Ho Choi, Hasi Huhe, Amantha Thathiah, P

Ethanol's interaction with BK channel α subunit residue K361 does not mediate behavioral responses to alcohol in mice

乙醇与 BK 通道 α 亚基残基 K361 的相互作用不会介导小鼠对酒精的行为反应

Agbonlahor Okhuarobo, Max Kreifeldt, Pauravi J Gandhi, Catherine Lopez, Briana Martinez, Kiera Fleck, Michal Bajo, Pushpita Bhattacharyya, Alex M Dopico, Marisa Roberto, Amanda J Roberts, Gregg E Homanics, Candice Contet

Knockdown of Tlr3 in dorsal striatum reduces ethanol consumption and acute functional tolerance in male mice

背侧纹状体中 Tlr3 的敲低可降低雄性小鼠的乙醇消耗和急性功能耐受性

Geoffrey A Dilly, Yuri A Blednov, Anna S Warden, Lubov Ezerskiy, Caleb Fleischer, Jesse D Plotkin, Shruti Patil, Elizabeth A Osterndorff-Kahanek, Jody Mayfield, R Dayne Mayfield, Gregg E Homanics, Robert O Messing

Changes in ethanol effects in knock-in mice expressing ethanol insensitive alpha1 and alpha2 glycine receptor subunits

表达乙醇不敏感的α1和α2甘氨酸受体亚基的敲入小鼠中乙醇效应的变化

San Martin, Loreto S; Armijo-Weingart, Lorena; Gallegos, Scarlet; Araya, Anibal; Homanics, Gregg E; Aguayo, Luis G