日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Do RND efflux pumps require protomeric cooperativity within the trimer to mediate antimicrobial resistance?

RND 外排泵是否需要三聚体内部的亚基协同作用来介导抗菌素耐药性?

Zhang, Zhemin; Klenotic, Philip A; Hung, Wei-Tse; Maharjan, Rakesh; Kundracik, Emma; Gregor, William D; Yu, Edward W

Structures of MmpL complexes reveal the assembly and mechanism of this family of transporters

MmpL复合物的结构揭示了该转运蛋白家族的组装和机制

Zhang, Zhemin; Maharjan, Rakesh; Gregor, William D; Klenotic, Philip A; Yu, Edward W

Cryo-EM structure of the Pseudomonas aeruginosa MexY multidrug efflux pump

铜绿假单胞菌 MexY 多药外排泵的冷冻电镜结构

Gregor, William D; Maharjan, Rakesh; Zhang, Zhemin; Chiaraviglio, Lucius; Sastry, Nithya; Cui, Meng; Kirby, James E; Yu, Edward W

The Plasmodium falciparum NCR1 transporter is an antimalarial target that exports cholesterol from the parasite's plasma membrane.

恶性疟原虫 NCR1 转运蛋白是一种抗疟靶点,可将胆固醇从寄生虫的质膜中输出

Zhang Zhemin, Lyu Meinan, Han Xu, Bandara Sepalika, Cui Meng, Istvan Eva S, Geng Xinran, Tringides Marios L, Gregor William D, Miyagi Masaru, Oberstaller Jenna, Adams John H, Zhang Youwei, Nieman Marvin T, von Lintig Johannes, Goldberg Daniel E, Yu Edward W

Structures of the mycobacterial MmpL4 and MmpL5 transporters provide insights into their role in siderophore export and iron acquisition

分枝杆菌MmpL4和MmpL5转运蛋白的结构揭示了它们在铁载体输出和铁吸收中的作用。

Maharjan, Rakesh; Zhang, Zhemin; Klenotic, Philip A; Gregor, William D; Tringides, Marios L; Cui, Meng; Purdy, Georgiana E; Yu, Edward W

Cryo-EM structure of the Mycobacterium smegmatis MmpL5-AcpM complex

耻垢分枝杆菌MmpL5-AcpM复合物的冷冻电镜结构

Maharjan, Rakesh; Zhang, Zhemin; Klenotic, Philip A; Gregor, William D; Purdy, Georgiana E; Yu, Edward W