日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Amygdala TDP-43 pathology is associated with behavioural dysfunction and ferritin accumulation in amyotrophic lateral sclerosis.

杏仁核 TDP-43 病理与肌萎缩侧索硬化症中的行为功能障碍和铁蛋白积累有关。

Rifai Olivia M, Waldron Fergal M, O'Shaughnessy Judi, Read Fiona L, Gilodi Martina, Pastore Annalisa, Shneider Neil A, Tartaglia Gian Gaetano, Zacco Elsa, Spence Holly, Gregory Jenna M

Metabolic signatures of ferritin and TDP-43 co-pathology provide a mechanistic basis for stratified therapeutic approaches in ALS

铁蛋白和TDP-43共病理的代谢特征为ALS的分层治疗策略提供了机制基础。

Spence, Holly; Read, Fiona L; Waldron, Fergal M; Gregory, Jenna M

Amyotrophic lateral sclerosis caused by TARDBP mutations: from genetics to TDP-43 proteinopathy

由TARDBP基因突变引起的肌萎缩侧索硬化症:从遗传学到TDP-43蛋白病

Balendra, Rubika; Sreedharan, Jemeen; Hallegger, Martina; Luisier, Raphaëlle; Lashuel, Hilal A; Gregory, Jenna M; Patani, Rickie

Large-scale RNA-Seq mining reveals ciclopirox olamine induces TDP-43 cryptic exons.

大规模 RNA-Seq 挖掘揭示环吡咯醇胺诱导 TDP-43 隐蔽外显子

Sinha Irika R, Sandal Parker S, Spence Holly, Burns Grace D, Mallika Aswathy Peethambaran, Abbasinejad Fatemeh, Irwin Katherine E, Cruz Anna Lourdes F, Wang Vania, Marx Shaelyn R, Rodríguez Josué Llamas, Langmead Ben, Gregory Jenna M, Wong Philip C, Ling Jonathan P

Quantitative Profiling of Nanoscopic Protein Aggregates Reveals Specific Fingerprint of TDP-43-Positive Assemblies in Motor Neuron Disease.

纳米级蛋白质聚集体的定量分析揭示了运动神经元疾病中 TDP-43 阳性聚集体的特定指纹。

Cox Dezerae, Burke Melanie, Milani Sara, White Matthew A, Waldron Fergal M, Böken Dorothea, Lobanova Evgeniia, Sreedharan Jemeen, Gregory Jenna M, Klenerman David

Clinicopathological analysis of NEK1 variants in amyotrophic lateral sclerosis

肌萎缩侧索硬化症中NEK1变异的临床病理分析

Rifai, Olivia M; Waldron, Fergal M; Sleibi, Danah; O'Shaughnessy, Judi; Leighton, Danielle J; Gregory, Jenna M

Consensus statement on exploring the Nexus between nutrition, brain health and dementia prevention

关于探索营养、大脑健康和痴呆症预防之间关系的共识声明

Johnstone, Alexandra M; Albanese, Emiliano; Crabtree, Daniel R; Dalile, Boushra; Grabrucker, Stefanie; Gregory, Jenna M; Grosso, Giuseppe; Holliday, Adrian; Hughes, Catherine; Itsiopoulos, Catherine; Mamo, John; McEvoy, Claire; Myint, Phyo Kyaw; Pereira, Leticia Radin; Vauzour, David; Siervo, Mario

Improving ALS detection and cognitive impairment stratification with attention-enhanced deep learning models

利用注意力增强型深度学习模型改进ALS检测和认知障碍分层

Xia, Yuqing; Gregory, Jenna M; Waldron, Fergal M; Spence, Holly; Vallejo, Marta

Distinct Cellular Phenotypes of Language and Executive Decline in Amyotrophic Lateral Sclerosis

肌萎缩侧索硬化症中语言和执行功能衰退的不同细胞表型

Petrescu, Joana; Roque, Cláudio Gouveia; Jackson, Christopher A; Daly, Aidan; Kang, Kristy; Casel, Obadele; Leung, Matthew; Reilly, Luke; Eschbach, Jacqueline; McDade, Karina; Gregory, Jenna M; Bonneau, Richard; Smith, Colin; Phatnani, Hemali

Skin TDP-43 pathology as a candidate biomarker for predicting amyotrophic lateral sclerosis decades prior to motor symptom onset

皮肤TDP-43病理可作为预测肌萎缩侧索硬化症的候选生物标志物,甚至在运动症状出现前数十年即可预测该疾病。

Waldron, Fergal M; Langerová, Tatiana; Rahmanova, Aydan; Read, Fiona L; Spence, Holly; Roberts, Kristine; Macleod, Angus D; Pattle, Samuel B; Hanna, Katie; Gregory, Jenna M