Treatment of a mutant KRAS lung cancer cell line with polyisoprenylated cysteinyl amide inhibitors activates the MAPK pathway, inhibits cell migration and induces apoptosis.
用聚异戊二烯化半胱氨酰胺抑制剂治疗突变型 KRAS 肺癌细胞系可激活 MAPK 通路,抑制细胞迁移并诱导细胞凋亡
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0312563
Gregory Matthew D, Ofosu-Asante Kweku, Lazarte Jassy Mary S, Puente Pablo E, Tawfeeq Nada, Belony Nadine, Huang Yong, Offringa Ite A, Lamango Nazarius S