日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel murine glioblastoma models that reflect the immunotherapy resistance profile of a human disease

反映人类疾病免疫疗法抵抗特征的新型鼠胶质母细胞瘤模型

Chao-Hsien Chen, Renee L Chin, Genevieve P Hartley, Spencer T Lea, Brian J Engel, Cheng-En Hsieh, Rishika Prasad, Jason Roszik, Takashi Shingu, Gregory A Lizee, Amy B Heimberger, Steven W Millward, Jian Hu, David S Hong, Michael A Curran

The CX3CL1-CX3CR1 chemokine axis can contribute to tumor immune evasion and blockade with a novel CX3CR1 monoclonal antibody enhances response to anti-PD-1 immunotherapy

CX3CL1-CX3CR1趋化因子轴可促进肿瘤免疫逃逸,而使用新型CX3CR1单克隆抗体阻断该轴可增强抗PD-1免疫疗法的疗效。

Apoorvi Chaudhri ,Xia Bu ,Yunfei Wang ,Michael Gomez ,James A Torchia ,Ping Hua ,Shao-Hsi Hung ,Michael A Davies ,Gregory A Lizee ,Ulrich von Andrian ,Patrick Hwu ,Gordon J Freeman