Transient centrosome loss in cultured prostate epithelial cells induces chromosomal instability to produce an oncogenic genotype that correlates with poor clinical outcomes
体外培养的前列腺上皮细胞中短暂的中心体丢失会诱导染色体不稳定,从而产生致癌基因型,该基因型与不良临床预后相关。
期刊:British Journal of Cancer
影响因子:6.8
doi:10.1038/s41416-025-03323-8
Yang, Jiawen; Ryniawec, John M; de Oliveira Pessoa, Diogo; Coope, Matthew R; Buster, Daniel W; Loertscher, Emily; Wang, Mengdie; Chen, Chen; Cress, Anne E; Padi, Megha; Rogers, Gregory C