Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors
共价靶向远端半胱氨酸残基以开发 CDK12 和 CDK13 抑制剂
期刊:Nature Chemical Biology
影响因子:12.9
doi:10.1038/nchembio.2166
Tinghu Zhang, Nicholas Kwiatkowski, Calla M Olson, Sarah E Dixon-Clarke, Brian J Abraham, Ann K Greifenberg, Scott B Ficarro, Jonathan M Elkins, Yanke Liang, Nancy M Hannett, Theresa Manz, Mingfeng Hao, Bartlomiej Bartkowiak, Arno L Greenleaf, Jarrod A Marto, Matthias Geyer, Alex N Bullock, Richard