日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Prototype timsOmni Platform Enables Confident Annotation of the Key Hypervariable CDR3 Regions of IgG Immunoglobulins Using Low- and High-Energy Electron-Based Fragmentation

timsOmni 平台原型利用低能和高能电子碎片化技术，实现了对 IgG 免疫球蛋白关键高变区 CDR3 的可靠注释

期刊:Analytical Chemistry
影响因子:6.7
doi:10.1021/acs.analchem.5c07288
Ollivier, Simon; Schuster, Dina; van Rijswijck, Danique M H; Stroganova, Iuliia; Smyrnakis, Athanasios; Fiala, Jan; Kosmopoulou, Mariangela; Suckau, Detlev; Pengelley, Stuart; Raether, Oliver; Greisch, Jean-François; Papanastasiou, Dimitris; Heck, Albert J R
IgG
免疫/内分泌
发表日期：2026
文献求助 收藏

Parallel Sequencing of the Two Arms on a Bispecific Antibody by Electron Capture Dissociation on a timsOmni Platform Reveals Several By-products in the Controlled Fab-arm Exchange Process

利用timsOmni平台上的电子捕获解离技术对双特异性抗体的两个臂进行平行测序，揭示了受控Fab臂交换过程中的几种副产物

期刊:Analytical Chemistry
影响因子:6.7
doi:10.1021/acs.analchem.5c07319
Stroganova, Iuliia; Ollivier, Simon; Radić, Laura; Smyrnakis, Athanasios; Kosmopoulou, Mariangela; Schinkel, Janke; Sliepen, Kwinten; Greisch, Jean-François; Heck, Albert J R
发表日期：2026
文献求助 收藏

Protein-Centric Analysis of Personalized Antibody Repertoires Using LC-MS-Based Fab-Profiling on a timsTOF

利用基于液相色谱-质谱联用技术的 timsTOF 平台进行 Fab 片段谱分析，实现以蛋白质为中心的个性化抗体库分析。

期刊:Journal of the American Society for Mass Spectrometry
影响因子:2.7
doi:10.1021/jasms.4c00076
Fiala, Jan; Schuster, Dina; Ollivier, Simon; Pengelley, Stuart; Lubeck, Markus; Busch, Florian; Jankevics, Andris; Raether, Oliver; Greisch, Jean-Francois; Heck, Albert J R
发表日期：2024
文献求助 收藏

An Orbitrap/Time-of-Flight Mass Spectrometer for Photofragment Ion Imaging and High-Resolution Mass Analysis of Native Macromolecular Assemblies

用于光碎片离子成像和天然大分子组装体高分辨率质量分析的 Orbitrap/飞行时间质谱仪

期刊:Journal of the American Society for Mass Spectrometry
影响因子:3.1
doi:10.1021/jasms.3c00053
Anjusha Mathew, Frans Giskes, Alexandros Lekkas, Jean-François Greisch, Gert B Eijkel, Ian G M Anthony, Kyle Fort, Albert J R Heck, Dimitris Papanastasiou, Alexander A Makarov, Shane R Ellis, Ron M A Heeren
信号转导
发表日期：2023
文献求助 收藏

Human plasma IgG1 repertoires are simple, unique, and dynamic

人类血浆 IgG1 库简单、独特且动态

期刊:Cell Systems
影响因子:9
doi:10.1016/j.cels.2021.08.008
Albert Bondt, Max Hoek, Sem Tamara, Bastiaan de Graaf, Weiwei Peng, Douwe Schulte, Danique M H van Rijswijck, Maurits A den Boer, Jean-François Greisch, Meri R J Varkila, Joost Snijder, Olaf L Cremer, Marc J M Bonten, Albert J R Heck
信号转导
Human
发表日期：2021
文献求助 收藏

Generating Informative Sequence Tags from Antigen-Binding Regions of Heavily Glycosylated IgA1 Antibodies by Native Top-Down Electron Capture Dissociation

利用天然自上而下电子捕获解离法从高度糖基化的IgA1抗体的抗原结合区生成信息序列标签

期刊:Journal of the American Society for Mass Spectrometry
影响因子:2.7
doi:10.1021/jasms.0c00461
Greisch, Jean-Francois; den Boer, Maurits A; Beurskens, Frank; Schuurman, Janine; Tamara, Sem; Bondt, Albert; Heck, Albert J R
IgA
发表日期：2021
文献求助 收藏

Enhancing Top-Down Analysis Using Chromophore-Assisted Infrared Multiphoton Dissociation from (Phospho)peptides to Protein Assemblies

利用发色团辅助红外多光子解离法增强从（磷酸化）肽到蛋白质组装体的自上而下的分析

期刊:Analytical Chemistry
影响因子:6.7
doi:10.1021/acs.analchem.0c03412
Jean-François Greisch, Saar A M van der Laarse, Albert J R Heck
表观遗传
发表日期：2020
文献求助 收藏

Benefits of Collisional Cross Section Assisted Precursor Selection (caps-PASEF) for Cross-linking Mass Spectrometry

碰撞截面辅助前体选择（caps-PASEF）在交联质谱分析中的优势

期刊:Molecular & Cellular Proteomics
影响因子:5.5
doi:10.1074/mcp.RA120.002094
Steigenberger, Barbara; van den Toorn, Henk W P; Bijl, Emiel; Greisch, Jean-François; Räther, Oliver; Lubeck, Markus; Pieters, Roland J; Heck, Albert J R; Scheltema, Richard A
发表日期：2020
文献求助 收藏

Divergent Coordination Chemistry: Parallel Synthesis of [2×2] Iron(II) Grid-Complex Tauto-Conformers

发散型配位化学：[2×2]铁(II)网格配合物互变构象异构体的平行合成

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.201603916
Schäfer, Bernhard; Greisch, Jean-François; Faus, Isabelle; Bodenstein, Tilmann; Šalitroš, Ivan; Fuhr, Olaf; Fink, Karin; Schünemann, Volker; Kappes, Manfred M; Ruben, Mario
发表日期：2016
文献求助 收藏