Greka Anna相关文献与解析，生知库 | 链接生命科学的每一步

Uncovering a novel role of focal adhesion and interferon-gamma in cellular rejection of kidney allografts at single cell resolution

在单细胞分辨率下揭示黏着斑和干扰素-γ在肾脏同种异体移植细胞排斥反应中的新作用

doi:10.3389/fimmu.2023.1139358

Halawi, Ahmad; El Kurdi, Abdullah B; Vernon, Katherine A; Solhjou, Zhabiz; Choi, John Y; Saad, Anis J; Younis, Nour K; Elfekih, Rania; Mohammed, Mostafa Tawfeek; Deban, Christa A; Weins, Astrid; Abdi, Reza; Riella, Leonardo V; De Serres, Sasha A; Cravedi, Paolo; Greka, Anna; Khoueiry, Pierre; Azzi, Jamil R

Further Exploration of the Benzimidazole Scaffold as TRPC5 Inhibitors: Identification of 1-Alkyl-2-(pyrrolidin-1-yl)-1H-benzo[d]imidazoles as Potent and Selective Inhibitors.

进一步探索苯并咪唑骨架作为 TRPC5 抑制剂：鉴定 1-烷基-2-(吡咯烷-1-基)-1H-苯并[d]咪唑作为强效选择性抑制剂

期刊:ChemMedChem

影响因子:3.4

doi:10.1002/cmdc.202200151

Sharma Swagat, L Pablo Juan, Tolentino Kirsten T, Gallegos Wacey, Hinman Jennifer, Beninato Madison, Asche MacKenzie, Greka Anna, Hopkins Corey R

骨科研究

发表日期：2022

文献求助收藏

Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity

疾病与健康状态下的脂质代谢：脂毒性的新兴调节因子

期刊:Molecular Cell

影响因子:16.6

doi:10.1016/j.molcel.2021.08.027

Yoon, Haejin; Shaw, Jillian L; Haigis, Marcia C; Greka, Anna

Principles of Spatial Transcriptomics Analysis: A Practical Walk-Through in Kidney Tissue

空间转录组学分析原理：肾脏组织实践指南

期刊:Frontiers in Physiology

影响因子:3.4

doi:10.3389/fphys.2021.809346

Noel, Teia; Wang, Qingbo S; Greka, Anna; Marshall, Jamie L

发表日期：2021

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Outcomes of patient self-referral for the diagnosis of several rare inherited kidney diseases

患者自行就诊诊断几种罕见遗传性肾病的结果

期刊:Genetics in Medicine

影响因子:6.2

doi:10.1038/s41436-019-0617-8

Bleyer, Anthony J; Kidd, Kendrah; Robins, Victoria; Martin, Lauren; Taylor, Abbigail; Santi, Annie; Tsoumas, Georgeanna; Hunt, Alese; Swain, Elizabeth; Abbas, Marwan; Akinbola, Ebun; Vidya, Sri; Moossavi, Shahriar; Bleyer, Anthony J Jr; Živná, Martina; Hartmannová, Hana; Hodaňová, Kateřina; Vyleťal, Petr; Votruba, Miroslav; Harden, Maegan; Blumenstiel, Brendan; Greka, Anna; Kmoch, Stanislav

发表日期：2020

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Charting a TRP to Novel Therapeutic Destinations for Kidney Diseases

绘制肾脏疾病新型治疗靶点的治疗路线图

期刊:Trends in Pharmacological Sciences

影响因子:19.9

doi:10.1016/j.tips.2019.10.001

Pablo, Juan Lorenzo; Greka, Anna

发表日期：2019

文献求助收藏

Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903

设计、合成和表征新型N-杂环-1-苄基-1H-苯并[d]咪唑-2-胺类化合物作为选择性TRPC5抑制剂，最终鉴定出选择性化合物AC1903。

期刊:Bioorganic & Medicinal Chemistry Letters

影响因子:2.2

doi:10.1016/j.bmcl.2018.12.007

Sharma, Swagat H; Pablo, Juan Lorenzo; Montesinos, Monica Suarez; Greka, Anna; Hopkins, Corey R

RPC5

发表日期：2019

文献求助收藏

Noninvasive Immunohistochemical Diagnosis and Novel MUC1 Mutations Causing Autosomal Dominant Tubulointerstitial Kidney Disease

无创免疫组织化学诊断及导致常染色体显性遗传性肾小管间质性肾病的新型MUC1突变

期刊:Journal of the American Society of Nephrology

影响因子:9.4

doi:10.1681/ASN.2018020180

Živná, Martina; Kidd, Kendrah; Přistoupilová, Anna; Barešová, Veronika; DeFelice, Mathew; Blumenstiel, Brendan; Harden, Maegan; Conlon, Peter; Lavin, Peter; Connaughton, Dervla M; Hartmannová, Hana; Hodaňová, Kateřina; Stránecký, Viktor; Vrbacká, Alena; Vyleťal, Petr; Živný, Jan; Votruba, Miroslav; Sovová, Jana; Hůlková, Helena; Robins, Victoria; Perry, Rebecca; Wenzel, Andrea; Beck, Bodo B; Seeman, Tomáš; Viklický, Ondřej; Rajnochová-Bloudíčková, Sylvie; Papagregoriou, Gregory; Deltas, Constantinos C; Alper, Seth L; Greka, Anna; Bleyer, Anthony J; Kmoch, Stanislav

Ann Chahroudi receives the 2025 ASCI/Marian W. Ropes, MD, Award

安·查鲁迪荣获2025年ASCI/玛丽安·W·罗普斯医学博士奖

FAF2 is a bifunctional regulator of peroxisomal homeostasis and saturated lipid responses.

FAF2 是过氧化物酶体稳态和饱和脂质反应的双功能调节因子

Uncovering a novel role of focal adhesion and interferon-gamma in cellular rejection of kidney allografts at single cell resolution

在单细胞分辨率下揭示黏着斑和干扰素-γ在肾脏同种异体移植细胞排斥反应中的新作用

Further Exploration of the Benzimidazole Scaffold as TRPC5 Inhibitors: Identification of 1-Alkyl-2-(pyrrolidin-1-yl)-1H-benzo[d]imidazoles as Potent and Selective Inhibitors.

进一步探索苯并咪唑骨架作为 TRPC5 抑制剂：鉴定 1-烷基-2-(吡咯烷-1-基)-1H-苯并[d]咪唑作为强效选择性抑制剂

Lipid metabolism in sickness and in health: Emerging regulators of lipotoxicity

疾病与健康状态下的脂质代谢：脂毒性的新兴调节因子

Principles of Spatial Transcriptomics Analysis: A Practical Walk-Through in Kidney Tissue

空间转录组学分析原理：肾脏组织实践指南

Outcomes of patient self-referral for the diagnosis of several rare inherited kidney diseases

患者自行就诊诊断几种罕见遗传性肾病的结果

Charting a TRP to Novel Therapeutic Destinations for Kidney Diseases

绘制肾脏疾病新型治疗靶点的治疗路线图

Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903

设计、合成和表征新型N-杂环-1-苄基-1H-苯并[d]咪唑-2-胺类化合物作为选择性TRPC5抑制剂，最终鉴定出选择性化合物AC1903。

Noninvasive Immunohistochemical Diagnosis and Novel MUC1 Mutations Causing Autosomal Dominant Tubulointerstitial Kidney Disease

无创免疫组织化学诊断及导致常染色体显性遗传性肾小管间质性肾病的新型MUC1突变