日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CK1δ over-expressing mice display ADHD-like behaviors, frontostriatal neuronal abnormalities and altered expressions of ADHD-candidate genes

CK1δ过表达小鼠表现出类似ADHD的行为、额纹状体神经元异常以及ADHD候选基因表达改变。

Zhou, Mingming; Gresack, Jodi; Cheng, Jia; Uryu, Kunihiro; Brichta, Lars; Greengard, Paul; Flajolet, Marc

Ahnak scaffolds p11/Anxa2 complex and L-type voltage-gated calcium channel and modulates depressive behavior

Ahnak 搭建 p11/Anxa2 复合物和 L 型电压门控钙通道并调节抑郁行为

Junghee Jin, Dionnet L Bhatti, Ko-Woon Lee, Lucian Medrihan, Jia Cheng, Jing Wei, Ping Zhong, Zhen Yan, Cassandra Kooiker, Claire Song, Jung-Hyuck Ahn, Gerald J Obermair, Amy Lee, Jodi Gresack, Paul Greengard, Yong Kim

AP-1 controls the p11-dependent antidepressant response

AP-1 控制 p11 依赖性抗抑郁反应

Revathy U Chottekalapanda, Salina Kalik, Jodi Gresack, Alyssa Ayala, Melanie Gao, Wei Wang, Sarah Meller, Ammar Aly, Anne Schaefer, Paul Greengard

DTI-identified microstructural changes in the gray matter of mice overexpressing CRF in the forebrain

DTI 检测到小鼠前脑过度表达 CRF 后灰质的微观结构变化

Deslauriers, Jessica; Toth, Mate; Scadeng, Miriam; McKenna, Benjamin S; Bussell, Robert; Gresack, Jodi; Rissman, Robert; Risbrough, Victoria B; Brown, Gregory G

FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory

FMRP 在 CA1 锥体神经元中具有细胞类型特异性作用,可调节自闭症相关转录本和昼夜节律记忆

Kirsty Sawicka, Caryn R Hale, Christopher Y Park, John J Fak, Jodi E Gresack, Sarah J Van Driesche, Jin Joo Kang, Jennifer C Darnell #, Robert B Darnell #

Excess Translation of Epigenetic Regulators Contributes to Fragile X Syndrome and Is Alleviated by Brd4 Inhibition

表观遗传调控因子过度翻译会导致脆性X综合征,而Brd4抑制剂可以缓解这一现象。

Erica Korb ,Margaret Herre ,Ilana Zucker-Scharff ,Jodi Gresack ,C David Allis ,Robert B Darnell

Relevance of the COPI complex for Alzheimer's disease progression in vivo

COPI 复合物与阿尔茨海默病体内进展的相关性

Karima Bettayeb, Basaraj V Hooli, Antonio R Parrado, Lisa Randolph, Dante Varotsis, Suvekshya Aryal, Jodi Gresack, Rudolph E Tanzi, Paul Greengard, Marc Flajolet

APP intracellular domain-WAVE1 pathway reduces amyloid-β production

APP 胞内结构域-WAVE1 通路减少淀粉样β蛋白的产生

Ilaria Ceglia, Christiane Reitz, Jodi Gresack, Jung-Hyuck Ahn, Victor Bustos, Marina Bleck, Xiaozhu Zhang, Grant Martin, Sanford M Simon, Angus C Nairn, Paul Greengard, Yong Kim

Alteration by p11 of mGluR5 localization regulates depression-like behaviors

p11 改变 mGluR5 定位可调节抑郁样行为

K-W Lee, L Westin, J Kim, J C Chang, Y-S Oh, B Amreen, J Gresack, M Flajolet, D Kim, A Aperia, Y Kim, P Greengard

Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease

酪氨酸磷酸酶 STEP 抑制剂可逆转阿尔茨海默病小鼠模型的认知缺陷

Jian Xu, Manavi Chatterjee, Tyler D Baguley, Jonathan Brouillette, Pradeep Kurup, Debolina Ghosh, Jean Kanyo, Yang Zhang, Kathleen Seyb, Chimezie Ononenyi, Ethan Foscue, George M Anderson, Jodi Gresack, Gregory D Cuny, Marcie A Glicksman, Paul Greengard, TuKiet T Lam, Lutz Tautz, Angus C Nairn, Jona