日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Do the redefined EUCAST susceptibility categories warrant adjustment of paediatric antibiotic dosages? Pragmatic physiologically based pharmacokinetic modelling of four commonly used agents

重新定义的欧盟抗菌药物敏感性测试委员会(EUCAST)药敏分级是否需要调整儿科抗生素剂量?基于生理学的实用药代动力学模型分析四种常用药物

de Hoop-Sommen, Marika A; Freriksen, Jolien J M; van der Heijden, Joyce E M; Jacobs, Jens; Oosterlaan, Yvette; Staring, Chantal M; van der Zeeuw, Shannon L; van der Zanden, Tjitske M; van der Bruggen, Jan-Tom; Quaak, Marjolijn S W; Vermont, Clementien; Wolfs, Tom F W; Brüggemann, Roger J M; Greupink, Rick; de Wildt, Saskia N

Validating Physiologically-Based Pharmacokinetic Models Using the Continuous Ranked Probability Score: Beyond Being Correct on Average

利用连续排序概率评分验证基于生理的药代动力学模型:超越平均正确性

Sluijterman, Laurens; van Borselen, Marjolein; Greupink, Rick; IntHout, Joanna

Sotalol Dose Optimization for Fetal Tachycardia: A Pregnancy Physiologically Based Pharmacokinetic Model Study

索他洛尔治疗胎儿心动过速的剂量优化:一项基于妊娠生理药代动力学模型的研究

van Hove, Hedwig; van der Heijden, Joyce E M; van Uden, Anne; Gijsen, Violette M G J; Greupink, Rick; de Wildt, Saskia N; van Drongelen, Joris

Physiologically based pharmacokinetic model combined with a clinical lactation study to determine doravirine concentrations in human breastmilk

基于生理药代动力学模型并结合临床哺乳研究,测定多拉韦林在人乳中的浓度

van der Wekken-Pas, Lena; Burger, David; Greupink, Rick; Colbers, Angela

Prescription of psychotropic drugs in persons with concurrent mental health and substance use disorders before and during the COVID-19 pandemic in Norway

挪威在新冠疫情前后对同时患有精神健康和物质使用障碍的人群开具精神药物的情况

Starokozhko, Viktoriia; Greupink, Rick; van de Broek, Petra; Soliman, Nashwa; Ghimire, Samiksha; de Graaf, Inge A M; Groothuis, Geny M M; Leonhardt, M; Lien, L

Targeted lipid nanoparticles to prevent trans-placental passage in the ex vivo human placental cotyledon perfusion model

靶向脂质纳米颗粒在离体人胎盘绒毛灌注模型中阻止跨胎盘转运

van Kammen, Caren; van Hove, Hedwig; Kapsokalyvas, Dimitrios; Greupink, Rick; Schiffelers, Raymond; Lely, Titia; Terstappen, Fieke

Physiologically Based Pharmacokinetic Modeling-Based Evaluation of Current Carbamazepine and Valproic Acid Dosing Guidelines for Pediatric Epilepsy Treatment

基于生理药代动力学模型的卡马西平和丙戊酸治疗儿童癫痫剂量指南评估

van der Heijden, Joyce E M; Gijsen, Violette; van Uden, Anne M; de Hoop-Sommen, Marika; Freriksen, Jolien J M; Jacobs, Elke; Greupink, Rick; de Wildt, Saskia N

Procognitive effects of methyl 2-amino-3-methoxybenzoate (or daopine) may involve the dorsal striatal anthranilic acid pathway and mutimetabolite-multitarget pharmacology

2-氨基-3-甲氧基苯甲酸甲酯(或达奥平)的促认知作用可能涉及背侧纹状体邻氨基苯甲酸通路和多代谢-多靶点药理学。

Bright, Yami; Amatdjais-Groenen, Helene I V; Verheij, Michel M M; van den Broek, Petra H H; Spoelder, Marcia; Maas, Dorien; Greupink, Rick; Martens, Gerard J M; Homberg, Judith R

Towards More Robust Evaluation of the Predictive Performance of Physiologically Based Pharmacokinetic Models: Using Confidence Intervals to Support Use of Model-Informed Dosing in Clinical Care

提高基于生理药代动力学模型预测性能的稳健性评估:利用置信区间支持在临床护理中使用模型指导的给药方案

van Borselen, Marjolein D; Sluijterman, Laurens Auke Æmiel; Greupink, Rick; de Wildt, Saskia N

Age-Specific ADME Gene Expression in Infant Intestinal Enteroids

婴儿肠道小肠类器官中年龄特异性 ADME 基因表达

Eva J Streekstra, Tom Scheer-Weijers, Michael Bscheider, Sabine Fuerst-Recktenwald, Adrian Roth, Sven C D van Ijzendoorn, Sanne Botden, Willem de Boode, Martijn W J Stommel, Rick Greupink, Frans G M Russel, Evita van de Steeg, Saskia N de Wildt