MKP-1 signaling events are required for early osteoclastogenesis in lineage defined progenitor populations by disrupting RANKL-induced NFATc1 nuclear translocation
MKP-1信号通路通过干扰RANKL诱导的NFATc1核转位,在谱系定义的祖细胞群中早期破骨细胞生成过程中发挥重要作用。
期刊:
影响因子:
doi:10.1016/j.bone.2013.11.012
Valerio, Michael S; Herbert, Bethany A; Griffin, Alfred C 3rd; Wan, Zhuang; Hill, Elizabeth G; Kirkwood, Keith L