日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Early life stress-induced depression reveals distinct region-specific modulation of unfolded protein response genes in the prefrontal cortex and hippocampus of rats

早期生活压力诱发的抑郁症揭示了大鼠前额叶皮层和海马体中未折叠蛋白反应基因的独特区域特异性调节

Griffin, Andrew Kirk; Roy, Bhaskar; Dwivedi, Yogesh

IMG-68. Corticosteroid-induced contrast-enhancing volume shrinkage and apparent diffusion coefficient reduction in glioblastoma MRI

IMG-68. 皮质类固醇诱导的胶质母细胞瘤MRI对比增强体积缩小和表观扩散系数降低

Awai, Hannah I; Yu, Elizabeth L; Ellis, Linda S; Schwimmer, Jeffrey B; Pyrpasopoulou, Athina; Zarras, Charalampos; Kouroupis, Dimitrios; Michailidou, Chrysi; Soukiouroglou, Prodromos; Pateinakis, Panagiotis; Mpani, Konstantina; Terzaki, Maria; Molyvas, Dimitrios; Vagdatli, Eleni; McKeown, Tara; Renzi, Samuele; Larouche, Valerie; Yeung, Rae; Hawkins, Cynthia; Bartels, Ute; Ramaswamy, Vijay; Bouffet, Eric; Tabori, Uri; Bennett, Julie; Das, Anirban; Nasir, N; Fatima, S; Awan, S; Zakariya, M; Arshad, A; Khalid, F; Aqeel, M; Nasir, N; Bhatia, Rohini; Siu, Catherine; Baker, Brock; Redmond, Kristin; Jackson, Christopher; Bettegowda, Chetan; Lim, Michael; Kleinberg, Lawrence; Lerner, Emily; Srinivasan, Ethan; Sankey, Eric; Grabowski, Matthew; Griffin, Andrew; Howell, Elizabeth; Otvos, Balint; Tsvankin, Vadim; Akit, Ahmet; Joshi, Krishna; Barnett, Gene; Fecci, Peter; Mohammadi, Alireza; Linder, Kathleen A; Zhou, Shiwei; Kauffman, Carol A; Miceli, Marisa H; Sanvito, Francesco; Kim, Asher; Raymond, Catalina; Teraishi, Ashley; Everson, Richard; Nghiemphu, Phioanh; Lai, Albert; Chong, Robert; Nathanson, David; Salamon, Noriko; Cloughesy, Timothy; Yao, Jingwen; Ellingson, Benjamin

SPAG7 deletion causes intrauterine growth restriction, resulting in adulthood obesity and metabolic dysfunction

SPAG7缺失导致宫内生长受限,从而导致成年期肥胖和代谢功能障碍

Stephen E Flaherty 3rd, Olivier Bezy, Brianna LaCarubba Paulhus, LouJin Song, Mary Piper, Jincheng Pang, Yoson Park, Shoh Asano, Yu-Chin Lien, John D Griffin, Andrew Robertson, Alan Opsahl, Dinesh Hirenallur Shanthappa, Youngwook Ahn, Evanthia Pashos, Rebecca A Simmons, Morris J Birnbaum, Zhidan Wu

Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01B malaria vaccine

延迟加强免疫可提高人体对RH5.1/AS01B疟疾疫苗的抗原特异性Ig和B细胞反应。

Carolyn M Nielsen,Jordan R Barrett,Christine Davis,Jonathan K Fallon,Cyndi Goh,Ashlin R Michell,Catherine Griffin,Andrew Kwok,Carolin Loos,Samuel Darko,Farida Laboune,Mehmet Tekman,Ababacar Diouf,Kazutoyo Miura,Joseph R Francica,Amy Ransier,Carole A Long,Sarah E Silk,Ruth O Payne,Angela M Minassian,Douglas A Lauffenburger,Robert A Seder,Daniel C Douek,Galit Alter,Simon J Draper

Mitochondrial variant enrichment from high-throughput single-cell RNA sequencing resolves clonal populations

通过高通量单细胞 RNA 测序富集线粒体变异可分辨克隆群体

Tyler E Miller, Caleb A Lareau, Julia A Verga, Erica A K DePasquale, Vincent Liu, Daniel Ssozi, Katalin Sandor, Yajie Yin, Leif S Ludwig, Chadi A El Farran, Duncan M Morgan, Ansuman T Satpathy, Gabriel K Griffin, Andrew A Lane, J Christopher Love, Bradley E Bernstein, Vijay G Sankaran, Peter van Gal

The novel persistent sodium current inhibitor PRAX-562 has potent anticonvulsant activity with improved protective index relative to standard of care sodium channel blockers.

新型持续性钠电流抑制剂 PRAX-562 具有强效抗惊厥活性,与标准钠通道阻滞剂相比,其保护指数有所提高

Kahlig Kristopher M, Scott Liam, Hatch Robert J, Griffin Andrew, Martinez Botella Gabriel, Hughes Zoë A, Wittmann Marion

Cilia proteins are biomarkers of altered flow in the vasculature

纤毛蛋白是血管系统血流改变的生物标志物

Ankan Gupta, Karthikeyan Thirugnanam, Madhan Thamilarasan, Ashraf M Mohieldin, Hadeel T Zedan, Shubhangi Prabhudesai, Meghan R Griffin, Andrew D Spearman, Amy Pan, Sean P Palecek, Huseyin C Yalcin, Surya M Nauli, Kevin R Rarick, Rahima Zennadi, Ramani Ramchandran

β-hydroxybutyrate accumulates in the rat heart during low-flow ischaemia with implications for functional recovery

β-羟基丁酸在低流量缺血期间在大鼠心脏中积聚,对功能恢复有影响

Ross T Lindsay, Sophie Dieckmann, Dominika Krzyzanska, Dominic Manetta-Jones, James A West, Cecilia Castro, Julian L Griffin, Andrew J Murray

Diabetic Kidney Disease Alters the Transcriptome and Function of Human Adipose-Derived Mesenchymal Stromal Cells but Maintains Immunomodulatory and Paracrine Activities Important for Renal Repair

糖尿病肾病会改变人类脂肪来源的间充质基质细胞的转录组和功能,但保持对肾脏修复至关重要的免疫调节和旁分泌活性

LaTonya J Hickson, Alfonso Eirin, Sabena M Conley, Timucin Taner, Xiaohui Bian, Ahmed Saad, Sandra M Herrmann, Ramila A Mehta, Travis J McKenzie, Todd A Kellogg, James L Kirkland, Tamar Tchkonia, Ishran M Saadiq, Hui Tang, Kyra L Jordan, Xiangyang Zhu, Mathew D Griffin, Andrew D Rule, Andre J van Wi

Discovery of the First Orally Available, Selective K(Na)1.1 Inhibitor: In Vitro and In Vivo Activity of an Oxadiazole Series

首个口服选择性K(Na)1.1抑制剂的发现:恶二唑系列化合物的体外和体内活性

Griffin, Andrew M; Kahlig, Kristopher M; Hatch, Robert John; Hughes, Zoë A; Chapman, Mark L; Antonio, Brett; Marron, Brian E; Wittmann, Marion; Martinez-Botella, Gabriel