Griffiths Jason I相关文献与解析，生知库

Singhal, Akshat; Zhao, Xiaoyu; Wall, Patrick; So, Emily; Calderini, Guido; Partin, Alexander; Koussa, Natasha; Vasanthakumari, Priyanka; Narykov, Oleksandr; Zhu, Yitan; Jones, Sara E; Abbas-Aghababazadeh, Farnoosh; Kadambat Nair, Sisira; Bélisle-Pipon, Jean-Christophe; Jayaram, Athmeya; Parker, Barbara A; Yeung, Kay T; Griffiths, Jason I; Weil, Ryan; Nath, Aritro; Haibe-Kains, Benjamin; Ideker, Trey

肿瘤

肿瘤免疫

发表日期：2025

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Mathematical models of intercellular signaling in breast cancer

乳腺癌细胞间信号传导的数学模型

期刊:Seminars in Cancer Biology

影响因子:15.7

doi:10.1016/j.semcancer.2025.01.005

Adler, Frederick R; Griffiths, Jason I

Cellular interactions within the immune microenvironment underpins resistance to cell cycle inhibition in breast cancers.

免疫微环境内的细胞相互作用是乳腺癌细胞对细胞周期抑制产生耐药性的基础

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-56279-x

Griffiths Jason I, Cosgrove Patrick A, Medina Eric F, Nath Aritro, Chen Jinfeng, Adler Frederick R, Chang Jeffrey T, Khan Qamar J, Bild Andrea H

System analysis links SMARCD3 regulons to growth signaling and MEK inhibitor response in everolimus-resistant ER+ breast cancer cells

系统分析表明，SMARCD3调控子与依维莫司耐药ER+乳腺癌细胞的生长信号传导和MEK抑制剂反应相关。

期刊:Cell Reports Medicine

影响因子:10.6

doi:10.1016/j.xcrm.2025.102425

Medina, Eric F; Farmaki, Elena; Griffiths, Jason I; Bild, Andrea H; Nath, Aritro

Blocking cancer-fibroblast mutualism inhibits proliferation of endocrine therapy resistant breast cancer.

阻断癌细胞与成纤维细胞的互利共生作用可抑制内分泌治疗耐药性乳腺癌的增殖

期刊:Molecular Systems Biology

影响因子:7.7

doi:10.1038/s44320-025-00104-6

Griffiths Jason I, Chi Feng, Farmaki Elena, Medina Eric F, Cosgrove Patrick A, Karimi Kimya L, Chen Jinfeng, Grolmusz Vince K, Adler Frederick R, Khan Qamar J, Nath Aritro, Chang Jeffrey T, Bild Andrea H

Mathematical modeling of the evolution of resistance and aggressiveness of high-grade serous ovarian cancer from patient CA-125 time series

基于患者 CA-125 时间序列的高级别浆液性卵巢癌耐药性和侵袭性演变的数学建模

期刊:PLoS Computational Biology

影响因子:3.6

doi:10.1371/journal.pcbi.1012073

Jitmana, Kanyarat; Griffiths, Jason I; Fereday, Sian; DeFazio, Anna; Bowtell, David; Adler, Frederick R

Phylogenetic inference from single-cell RNA-seq data

基于单细胞RNA测序数据的系统发育推断

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-023-39995-6

Liu, Xuan; Griffiths, Jason I; Bishara, Isaac; Liu, Jiayi; Bild, Andrea H; Chang, Jeffrey T

A machine learning framework for scRNA-seq UMI threshold optimization and accurate classification of cell types

一种用于单细胞RNA测序UMI阈值优化和细胞类型精确分类的机器学习框架

期刊:Frontiers in Genetics

影响因子:2.8

doi:10.3389/fgene.2022.982019

Bishara, Isaac; Chen, Jinfeng; Griffiths, Jason I; Bild, Andrea H; Nath, Aritro

Circulating immune cell phenotype dynamics reflect the strength of tumor-immune cell interactions in patients during immunotherapy

循环免疫细胞表型动态变化反映了免疫治疗期间患者体内肿瘤-免疫细胞相互作用的强度。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1918937117

Griffiths, Jason I; Wallet, Pierre; Pflieger, Lance T; Stenehjem, David; Liu, Xuan; Cosgrove, Patrick A; Leggett, Neena A; McQuerry, Jasmine A; Shrestha, Gajendra; Rossetti, Maura; Sunga, Gemalene; Moos, Philip J; Adler, Frederick R; Chang, Jeffrey T; Sharma, Sunil; Bild, Andrea H

Opportunities for improving cancer treatment using systems biology

利用系统生物学改善癌症治疗的机遇

期刊:Current Opinion in Systems Biology

影响因子:2.2

doi:10.1016/j.coisb.2019.10.018

Griffiths, Jason I; Cohen, Adam L; Jones, Veronica; Salgia, Ravi; Chang, Jeffrey T; Bild, Andrea H

The Hallmarks of Predictive Oncology

预测肿瘤学的标志

Mathematical models of intercellular signaling in breast cancer

乳腺癌细胞间信号传导的数学模型

Cellular interactions within the immune microenvironment underpins resistance to cell cycle inhibition in breast cancers.

免疫微环境内的细胞相互作用是乳腺癌细胞对细胞周期抑制产生耐药性的基础

System analysis links SMARCD3 regulons to growth signaling and MEK inhibitor response in everolimus-resistant ER+ breast cancer cells

系统分析表明，SMARCD3调控子与依维莫司耐药ER+乳腺癌细胞的生长信号传导和MEK抑制剂反应相关。

Blocking cancer-fibroblast mutualism inhibits proliferation of endocrine therapy resistant breast cancer.

阻断癌细胞与成纤维细胞的互利共生作用可抑制内分泌治疗耐药性乳腺癌的增殖

Mathematical modeling of the evolution of resistance and aggressiveness of high-grade serous ovarian cancer from patient CA-125 time series

基于患者 CA-125 时间序列的高级别浆液性卵巢癌耐药性和侵袭性演变的数学建模

Phylogenetic inference from single-cell RNA-seq data

基于单细胞RNA测序数据的系统发育推断

A machine learning framework for scRNA-seq UMI threshold optimization and accurate classification of cell types

一种用于单细胞RNA测序UMI阈值优化和细胞类型精确分类的机器学习框架

Circulating immune cell phenotype dynamics reflect the strength of tumor-immune cell interactions in patients during immunotherapy

循环免疫细胞表型动态变化反映了免疫治疗期间患者体内肿瘤-免疫细胞相互作用的强度。

Opportunities for improving cancer treatment using systems biology

利用系统生物学改善癌症治疗的机遇