日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Divergent trajectories to structural diversity impact patient survival in high grade serous ovarian cancer

结构多样性的不同发展轨迹会影响高级别浆液性卵巢癌患者的生存率

Ewing, Ailith; Meynert, Alison; Silk, Ryan; Aitken, Stuart; Bendixsen, Devin P; Churchman, Michael; Brown, Stuart L; Hamdan, Alhafidz; Mattocks, Joanne; Grimes, Graeme R; Ballinger, Tracy; Hollis, Robert L; Simon Herrington, C; Thomson, John P; Sherwood, Kitty; Parry, Thomas; Esiri-Bloom, Edward; Bartos, Clare; Croy, Ian; Ferguson, Michelle; Lennie, Mairi; McGoldrick, Trevor; McPhail, Neil; Siddiqui, Nadeem; Glasspool, Rosalind; Mackean, Melanie; Nussey, Fiona; McDade, Brian; Ennis, Darren; McMahon, Lynn; Matakidou, Athena; Dougherty, Brian; March, Ruth; Carl Barrett, J; McNeish, Iain A; Biankin, Andrew V; Roxburgh, Patricia; Gourley, Charlie; Semple, Colin A

Correction: Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops

更正:PRC1凝聚体的扩散会破坏多梳染色质结构域和环状结构。

Williamson, Iain; Boyle, Shelagh; Grimes, Graeme R; Friman, Elias T; Bickmore, Wendy A

In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma

体内患者遗传异质性建模揭示胆管癌治疗的新途径

Younger, Nicholas T; Wilson, Mollie L; Martinez Lyons, Anabel; Jarman, Edward J; Meynert, Alison M; Grimes, Graeme R; Gournopanos, Konstantinos; Waddell, Scott H; Tennant, Peter A; Wilson, David H; Guest, Rachel V; Wigmore, Stephen J; Acosta, Juan Carlos; Kendall, Timothy J; Taylor, Martin S; Sproul, Duncan; Mill, Pleasantine; Boulter, Luke

Structural Variants at the BRCA1/2 Loci are a Common Source of Homologous Repair Deficiency in High-grade Serous Ovarian Carcinoma

BRCA1/2基因位点的结构变异是高级别浆液性卵巢癌同源修复缺陷的常见原因

Ewing, Ailith; Meynert, Alison; Churchman, Michael; Grimes, Graeme R; Hollis, Robert L; Herrington, C Simon; Rye, Tzyvia; Bartos, Clare; Croy, Ian; Ferguson, Michelle; Lennie, Mairi; McGoldrick, Trevor; McPhail, Neil; Siddiqui, Nadeem; Dowson, Suzanne; Glasspool, Rosalind; Mackean, Melanie; Nussey, Fiona; McDade, Brian; Ennis, Darren; McMahon, Lynn; Matakidou, Athena; Dougherty, Brian; March, Ruth; Barrett, J Carl; McNeish, Iain A; Biankin, Andrew V; Roxburgh, Patricia; Gourley, Charlie; Semple, Colin A

Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip

Psip1/p52 通过激活 lncRNA Hottip 调控后部 Hoxa 基因。

Pradeepa, Madapura M; McKenna, Fionnuala; Taylor, Gillian C A; Bengani, Hemant; Grimes, Graeme R; Wood, Andrew J; Bhatia, Shipra; Bickmore, Wendy A

Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF.

人类β-防御素3影响与MyD88和TRIF相关的促炎通路的活性

Semple Fiona, MacPherson Heather, Webb Sheila, Cox Sarah L, Mallin Lucy J, Tyrrell Christine, Grimes Graeme R, Semple Colin A, Nix Matthew A, Millhauser Glenn L, Dorin Julia R

Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination

Ring1B 能够压缩染色质结构并抑制基因表达,且该过程不依赖于组蛋白泛素化。

Eskeland, Ragnhild; Leeb, Martin; Grimes, Graeme R; Kress, Clémence; Boyle, Shelagh; Sproul, Duncan; Gilbert, Nick; Fan, Yuhong; Skoultchi, Arthur I; Wutz, Anton; Bickmore, Wendy A