Destabilizing NF1 variants act in a dominant negative manner through neurofibromin dimerization
NF1 不稳定变体通过神经纤维蛋白二聚化以显性负性方式发挥作用。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2208960120
Young, Lucy C; Goldstein de Salazar, Ruby; Han, Sae-Won; Huang, Zi Yi Stephanie; Merk, Alan; Drew, Matthew; Darling, Joseph; Wall, Vanessa; Grisshammer, Reinhard; Cheng, Alice; Allison, Madeline R; Sale, Matthew J; Nissley, Dwight V; Esposito, Dominic; Ognjenovic, Jana; McCormick, Frank
