Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury
发现并优化一种高效、选择性强且口服生物利用度高的RARβ激动剂,用于潜在治疗神经损伤。
期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2019.02.011
Goncalves, Maria B; Clarke, Earl; Jarvis, Christopher I; Barret Kalindjian, S; Pitcher, Thomas; Grist, John; Hobbs, Carl; Carlstedt, Thomas; Jack, Julian; Brown, Jane T; Mills, Mark; Mumford, Peter; Borthwick, Alan D; Corcoran, Jonathan P T