日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury

发现并优化一种高效、选择性强且口服生物利用度高的RARβ激动剂,用于潜在治疗神经损伤。

Goncalves, Maria B; Clarke, Earl; Jarvis, Christopher I; Barret Kalindjian, S; Pitcher, Thomas; Grist, John; Hobbs, Carl; Carlstedt, Thomas; Jack, Julian; Brown, Jane T; Mills, Mark; Mumford, Peter; Borthwick, Alan D; Corcoran, Jonathan P T

Corrigendum to "Discovery and lead optimisation of a potent, selective and orally bioavailable RARβ agonist for the potential treatment of nerve injury" [Bioorg. Med. Chem. Lett. 29(8) (2019) 995-1000]

对“发现和先导化合物优化一种强效、选择性强且口服生物利用度高的 RARβ 激动剂用于潜在治疗神经损伤”的更正[Bioorg. Med. Chem. Lett. 29(8) (2019) 995-1000]

Goncalves, Maria B; Clarke, Earl; Jarvis, Christopher I; Kalindjian, S Barret; Pitcher, Thomas; Grist, John; Hobbs, Carl; Carlstedt, Thomas; Jack, Julian; Brown, Jane T; Mills, Mark; Mumford, Peter; Borthwick, Alan D; Corcoran, Jonathan P T

Retinoic acid synthesis by NG2 expressing cells promotes a permissive environment for axonal outgrowth

表达NG2的细胞合成视黄酸,从而促进轴突生长的有利环境。

Goncalves, Maria B; Wu, Yue; Trigo, Diogo; Clarke, Earl; Malmqvist, Tony; Grist, John; Hobbs, Carl; Carlstedt, Thomas P; Corcoran, Jonathan P T

Neuron-immune mechanisms contribute to pain in early stages of arthritis

神经免疫机制在关节炎早期阶段的疼痛中起着重要作用

Nieto, Francisco R; Clark, Anna K; Grist, John; Hathway, Gareth J; Chapman, Victoria; Malcangio, Marzia

Calcitonin gene-related peptide-expressing sensory neurons and spinal microglial reactivity contribute to pain states in collagen-induced arthritis

表达降钙素基因相关肽的感觉神经元和脊髓小胶质细胞反应性导致胶原诱导性关节炎的疼痛状态

Nieto, Francisco R; Clark, Anna K; Grist, John; Chapman, Victoria; Malcangio, Marzia

The role of G-protein receptor 84 in experimental neuropathic pain

G蛋白偶联受体84在实验性神经性疼痛中的作用

Nicol, Louise S C; Dawes, John M; La Russa, Federica; Didangelos, Athanasios; Clark, Anna K; Gentry, Clive; Grist, John; Davies, John B; Malcangio, Marzia; McMahon, Stephen B

Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain.

表达 CX3CR1 的单核细胞协调长春新碱诱导疼痛的发展

Old Elizabeth A, Nadkarni Suchita, Grist John, Gentry Clive, Bevan Stuart, Kim Ki-Wook, Mogg Adrian J, Perretti Mauro, Malcangio Marzia

A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat

比较RNA测序和外显子芯片技术在L5脊神经切断诱导大鼠神经性疼痛模型中全基因组转录谱分析中的应用

Perkins, James R; Antunes-Martins, Ana; Calvo, Margarita; Grist, John; Rust, Werner; Schmid, Ramona; Hildebrandt, Tobias; Kohl, Matthias; Orengo, Christine; McMahon, Stephen B; Bennett, David L H