日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Defining the Functional Role and Potential as an Immunotherapeutic Target of ALCAM in Neuroblastoma.

明确ALCAM在神经母细胞瘤中的功能作用及其作为免疫治疗靶点的潜力。

Lindsay Jarrett, Gaither Jonathan, Groff David, Samanta Minu, Kaufman Rebecca, Grossmann Liron, Hartnett Nicholas, Kendsersky Nathan, Mycek Emily A, Diskin Sharon J, Maris John M

A humanized anaplastic lymphoma kinase (ALK)-directed antibody-drug conjugate with pyrrolobenzodiazepine payload demonstrates efficacy in ALK-expressing cancers.

一种以吡咯并苯二氮卓类药物为有效载荷的人源化间变性淋巴瘤激酶(ALK)靶向抗体药物偶联物,在表达ALK的癌症中显示出疗效

Guerra Alberto D, Matkar Smita, Acholla Christina, Casey Colleen, Li Grant, Mazzeschi Martina, Patel Khushbu, Krytska Kateryna, Chen Chuan, Balyasny Skye, Kalna Joshua, Kamitsuka Paul, Gerelus Mark, Polkosnik Grace, Groff David, Mukherje Apratim, Adams Cynthia, Witek Gabriela, Hamilton Amber K, Martinez Daniel, Pogoriler Jennifer, Spear Timothy T, Li Yimei, Jung Piotr, Alvarado Diego, Lauriola Mattia, Maris John M, Wolpaw Adam J, Bosse Kristopher R, Dimitrov Dimiter, Mir Mustafa, Jelev Dontcho V, Mossé Yael P

Target antigen-displaying extracellular vesicles boost CAR T cell efficacy in cell and mouse models of neuroblastoma

靶向抗原展示的细胞外囊泡可增强CAR-T细胞在神经母细胞瘤细胞和鼠模型中的疗效

Giudice, Anna Maria; Matlaga, Stephanie; Roth, Sydney L; Pascual-Pasto, Guillem; Schürch, Patrick M; Rouin, Geoffrey; McIntyre, Brendan; Grothusen, Grant P; Cresswell-Clay, Evan; Shraim, Rawan; Groff, David; Zecchino, Vincent; Lombardi, Simona; Martinez, Daniel; Spruce, Lynn A; Brown, Elizabeth M; Fazelinia, Hossein; Henrickson, Sarah E; Nance, Jonas; Reynolds, C Patrick; Bosse, Kristopher R

Lineage dependence of the neuroblastoma surfaceome defines tumor cell state-dependent and -independent immunotherapeutic targets

神经母细胞瘤表面组的谱系依赖性决定了肿瘤细胞状态依赖性和非依赖性的免疫治疗靶点。

Kendsersky, Nathan M; Odrobina, Michal; Mabe, Nathaniel W; Farrel, Alvin; Grossmann, Liron; Tsang, Matthew; Groff, David; Wolpaw, Adam J; Narch, Alaa; Zammarchi, Francesca; van Berkel, Patrick H; Dang, Chi V; Mossé, Yaël P; Stegmaier, Kimberly; Maris, John M

D3-GPC2-Directed CAR T Cells Are Safe and Efficacious in Preclinical Models of Neuroblastoma and Small Cell Lung Cancer.

D3-GPC2 靶向 CAR T 细胞在神经母细胞瘤和小细胞肺癌的临床前模型中安全有效。

Giudice Anna Maria, Matlaga Stephanie, Roth Sydney L, Gladney Whitney, Groff David, Hofmann Ted J, McDaid Kendra S, Pascual-Pasto Guillem, McIntyre Brendan, Zecchino Vincent, Martinez Dan, Spear Timothy T, Wolpaw Adam J, Assenmacher Charles-Antoine, Radaelli Enrico, Pogoriler Jenny, Pawel Bruce, Barrett David, Grupp Stephan A, Maris John M, Bosse Kristopher R

The PLK4 inhibitor RP-1664 demonstrates potent single-agent efficacy in neuroblastoma models through a dual mechanism of sensitivity.

PLK4 抑制剂 RP-1664 通过双重敏感性机制在神经母细胞瘤模型中表现出强大的单药疗效

Maris John, Soria-Bretones Isabel, Casás-Selves Matias, Samanta Minu, Groff David, Murray Jayne, Fletcher Jamie, Farrel Alvin, Pastor Steven, Patel Khushbu, Goodfellow Elliot Goodfellow, Li Li, Caron Cathy, Shiwram Ariya, Kim Hyeyeon, Henry Danielle, Laterreur Nancy, Bowlan Julian, Krytska Kateryna, Neuhauser Steven, Stearns Timothy, Schubert Jeffrey, Wu Jinhua, Surrey Lea, Álvarez-Quilón Alejandro, Vallée Frédéric, Nejad Parham, Schonhoft Joseph, Li Joanna, Veloso Artur, Young Jordan, Hyer Marc, Morris Stephen, Mossé Yael P, Marshall Gary, Haber Michelle, Zimmermann Michal

Retraction Note: Cross-HLA targeting of intracellular oncoproteins with peptide-centric CARs

撤稿声明:利用肽中心CAR靶向细胞内癌蛋白的跨HLA

Yarmarkovich, Mark; Marshall, Quinlen F; Warrington, John M; Premaratne, Rasika; Farrel, Alvin; Groff, David; Li, Wei; di Marco, Moreno; Runbeck, Erin; Truong, Hau; Toor, Jugmohit S; Tripathi, Sarvind; Nguyen, Son; Shen, Helena; Noel, Tiffany; Church, Nicole L; Weiner, Amber; Kendsersky, Nathan; Martinez, Dan; Weisberg, Rebecca; Christie, Molly; Eisenlohr, Laurence; Bosse, Kristopher R; Dimitrov, Dimiter S; Stevanovic, Stefan; Sgourakis, Nikolaos G; Kiefel, Ben R; Maris, John M

Pre-clinical investigation of astatine-211-parthanatine for high-risk neuroblastoma

阿斯塔汀-211-帕他那汀治疗高危神经母细胞瘤的临床前研究

Makvandi, Mehran; Samanta, Minu; Martorano, Paul; Lee, Hwan; Gitto, Sarah B; Patel, Khushbu; Groff, David; Pogoriler, Jennifer; Martinez, Daniel; Riad, Aladdin; Dabagian, Hannah; Zaleski, Michael; Taghvaee, Tara; Xu, Kuiying; Lee, Ji Youn; Hou, Catherine; Farrel, Alvin; Batra, Vandana; Carlin, Sean D; Powell, Daniel J Jr; Mach, Robert H; Pryma, Daniel A; Maris, John M

The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models

靶向B7-H3的抗体-药物偶联物m276-SL-PBD对儿童癌症临床前实体瘤模型具有强效疗效

Kendsersky, Nathan M; Lindsay, Jarrett; Kolb, E Anders; Smith, Malcolm A; Teicher, Beverly A; Erickson, Stephen W; Earley, Eric J; Mosse, Yael P; Martinez, Daniel; Pogoriler, Jennifer; Krytska, Kateryna; Patel, Khushbu; Groff, David; Tsang, Matthew; Ghilu, Samson; Wang, Yifei; Seaman, Steven; Feng, Yang; Croix, Brad St; Gorlick, Richard; Kurmasheva, Raushan; Houghton, Peter J; Maris, John M

Diabetes Susceptibility Genes Pdx1 and Clec16a Function in a Pathway Regulating Mitophagy in β-Cells

糖尿病易感基因Pdx1和Clec16a在β细胞线粒体自噬调控通路中发挥作用

Soleimanpour, Scott A; Ferrari, Alana M; Raum, Jeffrey C; Groff, David N; Yang, Juxiang; Kaufman, Brett A; Stoffers, Doris A