日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metronidazole and ether derivatives target Helicobacter pylori via simultaneous stress induction and inhibition

甲硝唑及其醚类衍生物通过同时诱导和抑制应激反应来靶向幽门螺杆菌。

Fiedler, Michaela K; Pandler, Marianne S I; Gong, Ruolan; Fuchs, Sonja; Rox, Katharina; Friedrich, Verena; Pfeiffer, Dietmar; Singh, Dharmesh; Reinhardt, Till; Mibus, Cora; Huber, Matthias; Hess, Corinna R; Mejías-Luque, Raquel; Gerhard, Markus; Groll, Michael; Sieber, Stephan A

Structural Revision of the C(16) Sesquiterpene Hegelenether and the Mechanism of C6-Methylation in Terpene Biosynthesis

C(16)倍半萜Hegelenether的结构修正及萜类生物合成中C6-甲基化的机制

Li, Heng; Schnakenburg, Gregor; Groll, Michael; Dickschat, Jeroen S

Computational redesign and directed evolution of a lanthanide-dependent photoredox enzyme for enantioselective diol cleavage

利用计算方法重新设计和定向进化镧系元素依赖性光氧化还原酶实现对映选择性二醇裂解

Leiss-Maier, Florian; Behringer, Joshua; Mustafa, Ghulam; Heider, Anna; Mühlhofer, Rahel; Klein, Andreas S; Groll, Michael; Zeymer, Cathleen

Distal peptide elongation by a protease-like ligase and two distinct carrier proteins

蛋白酶样连接酶和两种不同的载体蛋白介导的远端肽链延伸

Gude, Finn; Bohne, Annkathrin; Dell, Maria; Franke, Jonathan; Dunbar, Kyle L; Groll, Michael; Hertweck, Christian

Hijacking a bacterial ABC transporter for genetic code expansion

利用细菌ABC转运蛋白进行遗传密码扩展

Iype, Tarun; Fottner, Maximilian; Böhm, Paul; Piedrafita, Carlos; Möller, Yannis; Groll, Michael; Lang, Kathrin

Studies of α',β'-Epoxyketone Synthesis by Small-Molecule Flavins and Flavoenzymes

小分子黄素和黄素酶对α',β'-环氧酮合成的研究

Walter, Alexandra; Kuttenlochner, Wolfgang; Eisenreich, Wolfgang; Yao, Chengyang; Groll, Michael; Storch, Golo

Molecular basis for azetidine-2-carboxylic acid biosynthesis.

氮杂环丁烷-2-羧酸生物合成的分子基础

Klaubert Tim J, Gellner Jonas, Bernard Charles, Effert Juliana, Lombard Carine, Kaila Ville R I, Bode Helge B, Li Yanyan, Groll Michael

The Isopropylstilbene Precursor Cinnamic Acid Inhibits Anthraquinone Pigment Production by Targeting AntI

异丙基芪前体肉桂酸通过靶向抗I受体抑制蒽醌色素的产生

Su, Li; Schmalhofer, Maximilian; Grammbitter, Gina L C; Paczia, Nicole; Glatter, Timo; Groll, Michael; Bode, Helge B

A Luminescence-Based Screening Platform for Lanthanide-Binding Peptides and Proteins

基于发光技术的镧系元素结合肽和蛋白质筛选平台

Klassen, Robert; Heider, Anna; Kugler, Hannah; Groll, Michael; Zeymer, Cathleen

Tailored SirReal-type inhibitors enhance SIRT2 inhibition through ligand stabilization and disruption of NAD(+) co-factor binding.

定制的 SirReal 型抑制剂通过配体稳定和破坏 NAD(+) 辅因子结合来增强 SIRT2 抑制作用

Wirawan Ricky, Frei Matthias, Heider Anna, Papenkordt Niklas, Friedrich Florian, Wein Thomas, Jung Manfred, Groll Michael, Huber Eva M, Bracher Franz