Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders
选择性磷酸二酯酶4D (PDE4D) 变构抑制剂的设计与合成及其在脆性X综合征和其他脑部疾病治疗中的应用
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.9b00193
Gurney, Mark E; Nugent, Richard A; Mo, Xuesheng; Sindac, Janice A; Hagen, Timothy J; Fox, David 3rd; O'Donnell, James M; Zhang, Chong; Xu, Ying; Zhang, Han-Ting; Groppi, Vincent E; Bailie, Marc; White, Ronald E; Romero, Donna L; Vellekoop, A Samuel; Walker, Joel R; Surman, Matthew D; Zhu, Lei; Campbell, Robert F
