日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HMGCS1 variants cause rigid spine syndrome amenable to mevalonic acid treatment in an animal model.

HMGCS1 变异体可导致脊柱僵硬综合征,在动物模型中可通过甲羟戊酸治疗治愈

Dofash Lein N H, Miles Lee B, Saito Yoshihiko, Rivas Eloy, Calcinotto Vanessa, Oveissi Sara, Serrano Rita J, Templin Rachel, Ramm Georg, Rodger Alison, Haywood Joel, Ingley Evan, Clayton Joshua S, Taylor Rhonda L, Folland Chiara L, Groth David, Hock Daniella H, Stroud David A, Gorokhova Svetlana, Donkervoort Sandra, Bönnemann Carsten G, Sud Malika, VanNoy Grace E, Mangilog Brian E, Pais Lynn, O'Donnell-Luria Anne, Madruga-Garrido Marcos, Scala Marcello, Fiorillo Chiara, Baratto Serena, Traverso Monica, Malfatti Edoardo, Bruno Claudio, Zara Federico, Paradas Carmen, Ogata Katsuhisa, Nishino Ichizo, Laing Nigel G, Bryson-Richardson Robert J, Cabrera-Serrano Macarena, Ravenscroft Gianina

Exploring the relationship between methylation of the cortisol receptor genes and brain and cognitive outcomes in individuals with elevated amyloid-β

探讨皮质醇受体基因甲基化与淀粉样β蛋白水平升高个体的大脑和认知结果之间的关系

Porter, Tenielle; Armstrong, Ayeisha Milligan; Milicic, Lidija; Vacher, Michael; Fernandez, Shane; O'Brien, Eleanor; Doré, Vincent; Bourgeat, Pierrick; Shishegar, Rosita; Xia, Ying; Rowe, Christopher; Villemagne, Victor; Maruff, Paul; Masters, Colin; Verdile, Giuseppe; Laws, Simon; Groth, David

Evaluation of Virtual Screening Strategies for the Identification of γ-Secretase Inhibitors and Modulators

评估虚拟筛选策略在鉴定γ-分泌酶抑制剂和调节剂中的应用

Ioppolo, Alicia; Eccles, Melissa; Groth, David; Verdile, Giuseppe; Agostino, Mark

SPON1 Is Associated with Amyloid-β and APOE ε4-Related Cognitive Decline in Cognitively Normal Adults

SPON1与认知功能正常成年人的β-淀粉样蛋白和APOE ε4相关的认知衰退有关

Fernandez, Shane; Burnham, Samantha C; Milicic, Lidija; Savage, Greg; Maruff, Paul; Peretti, Madeline; Sohrabi, Hamid R; Lim, Yen Ying; Weinborn, Michael; Ames, David; Masters, Colin L; Martins, Ralph N; Rainey-Smith, Stephanie; Rowe, Christopher C; Salvado, Olivier; Groth, David; Verdile, Giuseppe; Villemagne, Victor L; Porter, Tenielle; Laws, Simon M

Inflammation and Oral Contraceptive Use in Female Athletes Before the Rio Olympic Games

里约奥运会前女运动员的炎症和口服避孕药的使用情况

Brianna Larsen, Amanda Cox, Candice Colbey, Michael Drew, Helen McGuire, Barbara Fazekas de St Groth, David Hughes, Nicole Vlahovich, Gordon Waddington, Louise Burke, Bronwen Lundy, Nicholas West, Clare Minahan

COMT val158met is not associated with Aβ-amyloid and APOE ε4 related cognitive decline in cognitively normal older adults

COMT val158met 与认知功能正常的年长者中 Aβ 淀粉样蛋白和 APOE ε4 相关的认知衰退无关

Porter, Tenielle; Burnham, Samantha C; Milicic, Lidija; Savage, Greg; Maruff, Paul; Sohrabi, Hamid R; Peretti, Madeline; Lim, Yen Ying; Weinborn, Michael; Ames, David; Masters, Colin L; Martins, Ralph N; Rainey-Smith, Stephanie; Rowe, Christopher C; Salvado, Olivier; Groth, David; Verdile, Giuseppe; Villemagne, Victor L; Laws, Simon M

A Polygenic Risk Score Derived From Episodic Memory Weighted Genetic Variants Is Associated With Cognitive Decline in Preclinical Alzheimer's Disease

基于情景记忆加权遗传变异的多基因风险评分与临床前阿尔茨海默病患者的认知衰退相关

Porter, Tenielle; Burnham, Samantha C; Savage, Greg; Lim, Yen Ying; Maruff, Paul; Milicic, Lidija; Peretti, Madeline; Ames, David; Masters, Colin L; Martins, Ralph N; Rainey-Smith, Stephanie; Rowe, Christopher C; Salvado, Olivier; Taddei, Kevin; Groth, David; Verdile, Giuseppe; Villemagne, Victor L; Laws, Simon M

KIBRA is associated with accelerated cognitive decline and hippocampal atrophy in APOE ε4-positive cognitively normal adults with high Aβ-amyloid burden

KIBRA与携带APOE ε4基因且认知功能正常的成年人(伴有高Aβ淀粉样蛋白负荷)的认知功能加速衰退和海马萎缩相关。

Porter, Tenielle; Burnham, Samantha C; Doré, Vincent; Savage, Greg; Bourgeat, Pierrick; Begemann, Kimberly; Milicic, Lidija; Ames, David; Bush, Ashley I; Maruff, Paul; Masters, Colin L; Rowe, Christopher C; Rainey-Smith, Stephanie; Martins, Ralph N; Groth, David; Verdile, Giuseppe; Villemagne, Victor L; Laws, Simon M

The genetic architecture of the MHC class II region in British Texel sheep

英国特塞尔绵羊MHC II类区域的遗传结构

Ali, Alsagher O A; Stear, Abigail; Fairlie-Clarke, Karen; Brujeni, Gholamreza Nikbakht; Isa, N Mahiza Md; Salisi, M Shahrom Bin; Donskow-Łysoniewska, Katarzyna; Groth, David; Buitkamp, Johannes; Stear, Michael J

The Effects of Latrepirdine on Amyloid-β Aggregation and Toxicity

拉特吡啶对β-淀粉样蛋白聚集和毒性的影响

Porter, Tenielle; Bharadwaj, Prashant; Groth, David; Paxman, Adrian; Laws, Simon M; Martins, Ralph N; Verdile, Giuseppe