日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Small molecules restore mutant mitochondrial DNA polymerase activity

小分子可恢复突变线粒体DNA聚合酶活性

Sebastian Valenzuela ,Xuefeng Zhu ,Bertil Macao ,Mattias Stamgren ,Carol Geukens ,Paul S Charifson ,Gunther Kern ,Emily Hoberg ,Louise Jenninger ,Anja V Gruszczyk ,Seoeun Lee ,Katarina A S Johansson ,Javier Miralles Fusté ,Yonghong Shi ,S Jordan Kerns ,Laleh Arabanian ,Gabriel Martinez Botella ,Sofie Ekström ,Jeremy Green ,Andrew M Griffin ,Carlos Pardo-Hernández ,Thomas A Keating ,Barbara Küppers-Munther ,Nils-Göran Larsson ,Cindy Phan ,Viktor Posse ,Juli E Jones ,Xie Xie ,Simon Giroux ,Claes M Gustafsson ,Maria Falkenberg

Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation

促炎巨噬细胞通过复合物 I 的逆向电子传递产生线粒体来源的超氧化物,该超氧化物在 NLRP3 炎症小体激活过程中调节 IL-1β 的释放。

Alva M Casey ,Dylan G Ryan ,Hiran A Prag ,Suvagata Roy Chowdhury ,Eloïse Marques ,Keira Turner ,Anja V Gruszczyk ,Ming Yang ,Dane M Wolf ,Jan Lj Miljkovic ,Joyce Valadares ,Patrick F Chinnery ,Richard C Hartley ,Christian Frezza ,Julien Prudent ,Michael P Murphy

Assessment of left ventricular tissue mitochondrial bioenergetics in patients with stable coronary artery disease

稳定性冠状动脉疾病患者左心室组织线粒体生物能学评估

Richard E Jones, Anja V Gruszczyk #, Christina Schmidt #, Daniel J Hammersley, Lukas Mach, Michael Lee, Joyce Wong, Ming Yang, Suzan Hatipoglu, Amrit S Lota, Sam N Barnett, Rebecca Toscano-Rivalta, Ruth Owen, Shahzad Raja, Fabio De Robertis, Hassiba Smail, Anthony De-Souza, Ulrich Stock, Peter Kellm

Rapid fractionation of mitochondria from mouse liver and heart reveals in vivo metabolite compartmentation

小鼠肝脏和心脏线粒体的快速分离揭示了体内代谢物的区室化

Fay M Allen, Ana S H Costa, Anja V Gruszczyk, Georgina R Bates, Hiran A Prag, Efterpi Nikitopoulou, Carlo Viscomi, Christian Frezza, Andrew M James, Michael P Murphy

Low production of mitochondrial reactive oxygen species after anoxia and reoxygenation in turtle hearts

龟心脏缺氧和复氧后线粒体活性氧的产生量较低

Bundgaard, Amanda; Gruszczyk, Anja V; Prag, Hiran A; Williams, Catherine; McIntyre, Angela; Ruhr, Ilan M; James, Andrew M; Galli, Gina L J; Murphy, Michael P; Fago, Angela

Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation

UCP1 的半胱氨酸 253 调节能量消耗和性别依赖性脂肪组织炎症

Evanna L Mills ,Cathal Harmon ,Mark P Jedrychowski ,Haopeng Xiao ,Anja V Gruszczyk ,Gary A Bradshaw ,Nhien Tran ,Ryan Garrity ,Dina Laznik-Bogoslavski ,John Szpyt ,Hannah Prendeville ,Lydia Lynch ,Michael P Murphy ,Steven P Gygi ,Bruce M Spiegelman ,Edward T Chouchani

Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex

激动剂结合的Hsp90-XAP2-AHR胞质复合物的冷冻电镜结构

Jakub Gruszczyk,Loïc Grandvuillemin,Josephine Lai-Kee-Him,Matteo Paloni,Christos G Savva,Pierre Germain,Marina Grimaldi,Abdelhay Boulahtouf,Hok-Sau Kwong,Julien Bous,Aurélie Ancelin,Cherine Bechara,Alessandro Barducci,Patrick Balaguer,William Bourguet

AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology

AMPK 依赖的 MTFR1L 磷酸化调节线粒体形态

Lisa Tilokani, Fiona M Russell, Stevie Hamilton, Daniel M Virga, Mayuko Segawa, Vincent Paupe, Anja V Gruszczyk, Margherita Protasoni, Luis-Carlos Tabara, Mark Johnson, Hanish Anand, Michael P Murphy, D Grahame Hardie, Franck Polleux, Julien Prudent

Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury

缺氧成年小鼠心肌细胞缺血再灌注损伤模型中的线粒体代谢和生物能量功能

Anja V Gruszczyk, Alva M Casey, Andrew M James, Hiran A Prag, Nils Burger, Georgina R Bates, Andrew R Hall, Fay M Allen, Thomas Krieg, Kourosh Saeb-Parsy, Michael P Murphy

Assessment of the Effect of Selenium Supplementation on Production of Selected Cytokines in Women with Hashimoto's Thyroiditis

评估硒补充剂对桥本甲状腺炎女性患者特定细胞因子产生的影响

Jadwiga Kryczyk-Kozioł, Ewelina Prochownik, Anna Błażewska-Gruszczyk, Marian Słowiaczek, Qian Sun, Lutz Schomburg, Ewa Ochab, Mirosław Bartyzel, Paweł Zagrodzki