日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The molecular basis of Abelson kinase regulation by its αI-helix

Abelson 激酶通过其 αI-螺旋调控的分子基础

Johannes Paladini #, Annalena Maier #, Judith Maria Habazettl, Ines Hertel, Rajesh Sonti, Stephan Grzesiek

Imatinib disassembles the regulatory core of Abelson kinase by binding to its ATP site and not by binding to its myristoyl pocket

伊马替尼通过结合 ATP 位点而不是肉豆蔻酰口袋来分解 Abelson 激酶的调节核心

Stephan Grzesiek, Johannes Paladini, Judith Habazettl, Rajesh Sonti

Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist

趋化因子激动剂激活 CC 趋化因子受体 5 的结构基础

Polina Isaikina, Ching-Ju Tsai, Nikolaus Dietz, Filip Pamula, Anne Grahl, Kenneth N Goldie, Ramon Guixà-González, Camila Branco, Marianne Paolini-Bertrand, Nicolas Calo, Fabrice Cerini, Gebhard F X Schertler, Oliver Hartley, Henning Stahlberg, Timm Maier, Xavier Deupi, Stephan Grzesiek

A high-resolution description of β1-adrenergic receptor functional dynamics and allosteric coupling from backbone NMR

从主链 NMR 高分辨率描述 β1-肾上腺素受体功能动力学和变构耦合

Anne Grahl, Layara Akemi Abiko, Shin Isogai, Timothy Sharpe, Stephan Grzesiek

Deuterium induces a distinctive Escherichia coli proteome that correlates with the reduction in growth rate

氘诱导大肠杆菌产生独特的蛋白质组,与生长率降低相关

Christian Opitz, Erik Ahrné, Kenneth N Goldie, Alexander Schmidt, Stephan Grzesiek

Put Your Lights On: Electrocution As a Cause of an Unexplained Fall and Loss of Consciousness

打开灯:触电是导致不明原因跌倒和失去意识的原因之一

Grzesiek, Magdalena; Ellmann, Christina; Ditting, Tilmann

Cyclic di-GMP differentially tunes a bacterial flagellar motor through a novel class of CheY-like regulators

环二鸟苷酸通过一类新型 CheY 样调节器对细菌鞭毛马达进行差异调节

Jutta Nesper #, Isabelle Hug #, Setsu Kato #, Chee-Seng Hee #, Judith Maria Habazettl, Pablo Manfredi, Stephan Grzesiek, Tilman Schirmer, Thierry Emonet, Urs Jenal

Comprehensive structural and dynamical view of an unfolded protein from the combination of single-molecule FRET, NMR, and SAXS

通过单分子 FRET、NMR 和 SAXS 的组合,全面了解未折叠蛋白质的结构和动力学

Mikayel Aznauryan, Leonildo Delgado, Andrea Soranno, Daniel Nettels, Jie-Rong Huang, Alexander M Labhardt, Stephan Grzesiek, Benjamin Schuler

WhiB7, an Fe-S-dependent transcription factor that activates species-specific repertoires of drug resistance determinants in actinobacteria

WhiB7 是一种 Fe-S 依赖性转录因子,可激活放线菌中物种特异性的耐药性决定簇。

Santiago Ramón-García ,Carol Ng, Pernille R Jensen, Manisha Dosanjh, Jan Burian, Rowan P Morris, Marc Folcher, Lindsay D Eltis, Stephan Grzesiek, Liem Nguyen, Charles J Thompson

NMR reveals the allosteric opening and closing of Abelson tyrosine kinase by ATP-site and myristoyl pocket inhibitors

NMR 揭示了 ATP 位点和肉豆蔻酰口袋抑制剂对 Abelson 酪氨酸激酶的变构打开和关闭

Lukasz Skora, Jürgen Mestan, Doriano Fabbro, Wolfgang Jahnke, Stephan Grzesiek