日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus.

tRNA 低修饰通过激活交叉通路控制系统促进烟曲霉产生 5-氟胞嘧啶抗性

Bruch Alexander, Lazarova Valentina, Berg Maximilian, Krüger Thomas, Schäuble Sascha, Kelani Abdulrahman A, Mertens Birte, Lehenberger Pamela, Kniemeyer Olaf, Kaiser Stefanie, Panagiotou Gianni, Gsaller Fabio, Blango Matthew G

Simultaneous multigene integration in Aspergillus fumigatus using CRISPR/Cas9 and endogenous counter-selectable markers

利用 CRISPR/Cas9 和内源性反向选择标记在烟曲霉中同时进行多基因整合

Sastré-Velásquez, Luis Enrique; Mach, Natalia; Mertens, Birte; Kühbacher, Alexander; Merschak, Petra; Dallemulle, Alex; Lechner, Lukas; Baldin, Clara; Diallinas, George; Gsaller, Fabio

The transcription factor RttA contributes to sterol regulation and azole resistance in Aspergillus fumigatus

转录因子RttA参与烟曲霉的甾醇调节和唑类耐药性

Birštonas, Lukas; Hortschansky, Peter; Bauer, Ingo; Alcanzo, Ervin M; Kühbacher, Alexander; Mertens, Birte; Müller, Christoph; Brakhage, Axel A; Gsaller, Fabio

Development and optimization of large-scale approaches to identify iron-related genes in Aspergillus fumigatus.

开发和优化大规模方法以识别烟曲霉中的铁相关基因

Baldin Clara, Binder Ulrike, Scheler Jakob, Werner Ernst R, Gsaller Fabio, Bromley Michael J, Haas Hubertus

Anti-Aspergillus activities of olorofim at sub-MIC levels during early-stage growth

在曲霉菌生长早期阶段,低于最低抑菌浓度(MIC)的奥洛芬具有抗曲霉菌活性。

Kühbacher, Alexander; Birch, Mike; Oliver, Jason D; Gsaller, Fabio

The cytochrome P450 reductase CprA is a rate-limiting factor for Cyp51A-mediated azole resistance in Aspergillus fumigatus

细胞色素P450还原酶CprA是烟曲霉中Cyp51A介导的唑类耐药性的限速因子。

Kühbacher, Alexander; Merschak, Petra; Haas, Hubertus; Liebl, Maximilian; Müller, Christoph; Gsaller, Fabio

The fungal expel of 5-fluorocytosine derived fluoropyrimidines mitigates its antifungal activity and generates a cytotoxic environment

真菌排出5-氟胞嘧啶衍生的氟嘧啶会减弱其抗真菌活性并产生细胞毒性环境。

Sastré-Velásquez, Luis Enrique; Dallemulle, Alex; Kühbacher, Alexander; Baldin, Clara; Alcazar-Fuoli, Laura; Niedrig, Anna; Müller, Christoph; Gsaller, Fabio

Azole Resistance-Associated Regulatory Motifs within the Promoter of cyp51A in Aspergillus fumigatus

烟曲霉cyp51A启动子内的唑类耐药相关调控基序

Kühbacher, Alexander; Peiffer, Mandy; Hortschansky, Peter; Merschak, Petra; Bromley, Michael J; Haas, Hubertus; Brakhage, Axel A; Gsaller, Fabio

Modular Inducible Multigene Expression System for Filamentous Fungi

用于丝状真菌的模块化诱导多基因表达系统

Baldin, Clara; Kühbacher, Alexander; Merschak, Petra; Wagener, Johannes; Gsaller, Fabio

Antifungal Siderophore Conjugates for Theranostic Applications in Invasive Pulmonary Aspergillosis Using Low-Molecular TAFC Scaffolds

利用低分子TAFC支架制备用于侵袭性肺曲霉病诊疗的抗真菌铁载体缀合物

Pfister, Joachim; Petrik, Milos; Bendova, Katerina; Matuszczak, Barbara; Binder, Ulrike; Misslinger, Matthias; Kühbacher, Alexander; Gsaller, Fabio; Haas, Hubertus; Decristoforo, Clemens