FXa-mediated PAR-2 promotes the efficacy of immunotherapy for hepatocellular carcinoma through immune escape and anoikis resistance by inducing PD-L1 transcription
FXa介导的PAR-2通过诱导PD-L1转录,促进免疫逃逸和抗凋亡,从而提高肝细胞癌免疫疗法的疗效。
期刊:Journal for ImmunoTherapy of Cancer
影响因子:10.6
doi:10.1136/jitc-2024-009565
Li, Xuemei; Gao, Lei; Wang, Bofang; Hu, Jike; Yu, Yang; Gu, Baohong; Xiang, Lin; Li, Xiaomei; Li, Haiyuan; Zhang, Tao; Wang, Yunpeng; Ma, Chenhui; Dong, Jiahong; Lu, Jianrong; Lucas, Alexandra; Chen, Hao
肿瘤
凋亡
表观遗传
肿瘤免疫
PD-L1
细胞生物学
免疫/内分泌