日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Counterion docking: a general approach to reducing energetic disorder in doped polymeric semiconductors

反离子对接：减少掺杂聚合物半导体中能量无序的通用方法

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-024-49208-x
Miao Xiong #, Xin-Yu Deng #, Shuang-Yan Tian, Kai-Kai Liu, Yu-Hui Fang, Juan-Rong Wang, Yunfei Wang, Guangchao Liu, Jupeng Chen, Diego Rosas Villalva, Derya Baran, Xiaodan Gu, Ting Lei
信号转导
发表日期：2024
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The milk-derived fusion peptide, ACFP, suppresses the growth of primary human ovarian cancer cells by regulating apoptotic gene expression and signaling pathways

乳源性融合肽ACFP通过调节凋亡基因表达和信号通路抑制原代人卵巢癌细胞的生长。

期刊:BMC Cancer
影响因子:3.4
doi:10.1186/s12885-016-2281-6
Juan Zhou,Mengjing Zhao,Yigui Tang,Jing Wang,Cai Wei,Fang Gu,Ting Lei,Zhiwu Chen,Yide Qin
卵巢癌
Human
信号转导
细胞生物学
信号转导
肿瘤
表观遗传
凋亡
发表日期：2016
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Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation

PGAM1 的 Tyr26 位点磷酸化通过稳定其活性构象，为肿瘤提供代谢优势。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/ncomms2759
Hitosugi, Taro; Zhou, Lu; Fan, Jun; Elf, Shannon; Zhang, Liang; Xie, Jianxin; Wang, Yi; Gu, Ting-Lei; Alečković, Masa; LeRoy, Gary; Kang, Yibin; Kang, Hee-Bum; Seo, Jae-Ho; Shan, Changliang; Jin, Peng; Gong, Weimin; Lonial, Sagar; Arellano, Martha L; Khoury, Hanna J; Chen, Georgia Z; Shin, Dong M; Khuri, Fadlo R; Boggon, Titus J; Kang, Sumin; He, Chuan; Chen, Jing
肿瘤
肿瘤免疫
信号转导
代谢
磷酸化
发表日期：2013
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The prometastatic ribosomal S6 kinase 2-cAMP response element-binding protein (RSK2-CREB) signaling pathway up-regulates the actin-binding protein fascin-1 to promote tumor metastasis

促转移的核糖体S6激酶2-cAMP反应元件结合蛋白（RSK2-CREB）信号通路上调肌动蛋白结合蛋白fascin-1，从而促进肿瘤转移。

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M113.500561
Li, Dan; Jin, Lingtao; Alesi, Gina N; Kim, Young-Mee; Fan, Jun; Seo, Jae Ho; Wang, Dongsheng; Tucker, Meghan; Gu, Ting-Lei; Lee, Benjamin H; Taunton, Jack; Magliocca, Kelly R; Chen, Zhuo G; Shin, Dong M; Khuri, Fadlo R; Kang, Sumin
肿瘤
肿瘤免疫
信号转导
CREB
GPCR/Calcium/cAMP
发表日期：2013
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Tyrosine phosphorylation of lactate dehydrogenase A is important for NADH/NAD(+) redox homeostasis in cancer cells

乳酸脱氢酶A的酪氨酸磷酸化对于癌细胞中NADH/NAD(+)氧化还原稳态至关重要。

期刊:Molecular and Cellular Biology
影响因子:2.7
doi:10.1128/MCB.06120-11
Fan, Jun; Hitosugi, Taro; Chung, Tae-Wook; Xie, Jianxin; Ge, Qingyuan; Gu, Ting-Lei; Polakiewicz, Roberto D; Chen, Georgia Z; Boggon, Titus J; Lonial, Sagar; Khuri, Fadlo R; Kang, Sumin; Chen, Jing
肿瘤
肿瘤免疫
信号转导
磷酸化
细胞生物学
发表日期：2011
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Survey of activated FLT3 signaling in leukemia

白血病中激活的FLT3信号通路调查

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0019169
Gu, Ting-lei; Nardone, Julie; Wang, Yi; Loriaux, Marc; Villén, Judit; Beausoleil, Sean; Tucker, Meghan; Kornhauser, Jon; Ren, Jianmin; MacNeill, Joan; Gygi, Steven P; Druker, Brian J; Heinrich, Michael C; Rush, John; Polakiewicz, Roberto D
白血病
信号转导
FLT3
发表日期：2011
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p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells

p90核糖体S6激酶2促进人头颈部鳞状细胞癌细胞的侵袭和转移

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI40582
Kang, Sumin; Elf, Shannon; Lythgoe, Katherine; Hitosugi, Taro; Taunton, Jack; Zhou, Wei; Xiong, Li; Wang, Dongsheng; Muller, Susan; Fan, Songqing; Sun, Shi-Yong; Marcus, Adam I; Gu, Ting-Lei; Polakiewicz, Roberto D; Chen, Zhuo Georgia; Khuri, Fadlo R; Shin, Dong M; Chen, Jing
信号转导
细胞生物学
肿瘤
肿瘤免疫
发表日期：2010
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Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth

酪氨酸磷酸化抑制PKM2，从而促进瓦博格效应和肿瘤生长。

期刊:Science Signaling
影响因子:6.6
doi:10.1126/scisignal.2000431
Hitosugi, Taro; Kang, Sumin; Vander Heiden, Matthew G; Chung, Tae-Wook; Elf, Shannon; Lythgoe, Katherine; Dong, Shaozhong; Lonial, Sagar; Wang, Xu; Chen, Georgia Z; Xie, Jianxin; Gu, Ting-Lei; Polakiewicz, Roberto D; Roesel, Johannes L; Boggon, Titus J; Khuri, Fadlo R; Gilliland, D Gary; Cantley, Lewis C; Kaufman, Jonathan; Chen, Jing
信号转导
磷酸化
肿瘤
肿瘤免疫
发表日期：2009
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Disease mutations in RUNX1 and RUNX2 create nonfunctional, dominant-negative, or hypomorphic alleles.

RUNX1 和 RUNX2 中的致病突变会产生无功能、显性负性或功能减弱的等位基因

期刊:EMBO Journal
影响因子:8.3
doi:10.1038/sj.emboj.7601568
Matheny Christina J, Speck Maren E, Cushing Patrick R, Zhou Yunpeng, Corpora Takeshi, Regan Michael, Newman Miki, Roudaia Liya, Speck Caroline L, Gu Ting-Lei, Griffey Stephen M, Bushweller John H, Speck Nancy A
RUNX2
RUNX1
发表日期：2007
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Combination of rapamycin and protein tyrosine kinase (PTK) inhibitors for the treatment of leukemias caused by oncogenic PTKs.

雷帕霉素与蛋白酪氨酸激酶 (PTK) 抑制剂联合治疗致癌 PTK 引起的白血病

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.0400063101
Mohi M Golam, Boulton Christina, Gu Ting-Lei, Sternberg David W, Neuberg Donna, Griffin James D, Gilliland D Gary, Neel Benjamin G
肿瘤
白血病
发表日期：2004
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