日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

New allosteric modulators of molecular chaperone TRAP1 from the integration of computational biology, medicinal chemistry, and biophysics

结合计算生物学、药物化学和生物物理学，发现分子伴侣TRAP1的新型变构调节剂

期刊:Cell Stress & Chaperones
影响因子:3.2
doi:10.1016/j.cstres.2026.100162
Guarra, Federica; Komarov, Denis; Ciamarone, Andrea; Torielli, Luca; Previtali, Viola; Margaroli, Natasha; Romeo, Elisa; La Spina, Martina; Sbuelz, Francesca; Laquatra, Claudio; Veronesi, Marina; Lolicato, Marco; Arrigoni, Cristina; Moroni, Elisabetta; Serapian, Stefano A; Girotto, Stefania; Rasola, Andrea; Colombo, Giorgio
TRAP1
发表日期：2026
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Pathogenic mutation impairs functional dynamics of Hsp60 in mono- and oligomeric states

致病性突变会损害Hsp60在单体和寡聚状态下的功能动力学。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-57958-5
Torielli, Luca; Guarra, Federica; Shao, Hao; Gestwicki, Jason E; Serapian, Stefano A; Colombo, Giorgio
发表日期：2025
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Disulfide-mediated tetramerization of TRAP1 fosters its antioxidant and pro-neoplastic activities.

TRAP1 的二硫键介导的四聚化促进其抗氧化和促肿瘤活性

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2025.103677
Faienza Fiorella, Laquatra Claudio, Castelli Matteo, Matrullo Gianmarco, Rizza Salvatore, Guarra Federica, Dashtmian Azam Roshani, Magro Alessia, Giglio Paola, Pecorari Chiara, Ferrone Lavinia, Moroni Elisabetta, Pacello Francesca, Battistoni Andrea, Colombo Giorgio, Rasola Andrea, Filomeni Giuseppe
肿瘤
肿瘤免疫
发表日期：2025
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Point mutations of the mitochondrial chaperone TRAP1 affect its functions and pro-neoplastic activity.

线粒体分子伴侣TRAP1的点突变会影响其功能和促肿瘤活性

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07467-6
Laquatra Claudio, Magro Alessia, Guarra Federica, Lambrughi Matteo, Ferrone Lavinia, Fracasso Giulio, Bacchin Melissa, La Spina Martina, Moroni Elisabetta, Papaleo Elena, Colombo Giorgio, Rasola Andrea
肿瘤
线粒体
发表日期：2025
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Density Functional Theory Calculations to Investigate the Role Played by an Aspartate Dyad in Hsp60-Catalyzed ATP Hydrolysis

利用密度泛函理论计算研究天冬氨酸二元体在Hsp60催化ATP水解中的作用

期刊:Journal of Physical Chemistry Letters
影响因子:4.6
doi:10.1021/acs.jpclett.5c02351
Torielli, Luca; Guarra, Federica; Serapian, Stefano A; Colombo, Giorgio
发表日期：2025
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Cracking the chaperone code through the computational microscope

通过计算显微镜破解伴侣密码

期刊:Cell Stress & Chaperones
影响因子:3.2
doi:10.1016/j.cstres.2024.08.001
Guarra, Federica; Sciva, Cristiano; Bonollo, Giorgio; Pasala, Chiranjeevi; Chiosis, Gabriela; Moroni, Elisabetta; Colombo, Giorgio
发表日期：2024
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Computational Methods in Immunology and Vaccinology: Design and Development of Antibodies and Immunogens

免疫学和疫苗学中的计算方法：抗体和免疫原的设计与开发

期刊:Journal of Chemical Theory and Computation
影响因子:5.5
doi:10.1021/acs.jctc.3c00513
Guarra, Federica; Colombo, Giorgio
Immunology/Inflammation
免疫/内分泌
发表日期：2023
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(124) I Radiolabeling of a Au(III) -NHC Complex for In Vivo Biodistribution Studies

（124）I. Au(III)-NHC配合物的放射性标记及其在体内生物分布研究中的应用

期刊:Angewandte Chemie-International Edition
影响因子:16.9
doi:10.1002/anie.202008046
Guarra, Federica; Terenzi, Alessio; Pirker, Christine; Passannante, Rossana; Baier, Dina; Zangrando, Ennio; Gómez-Vallejo, Vanessa; Biver, Tarita; Gabbiani, Chiara; Berger, Walter; Llop, Jordi; Salassa, Luca
发表日期：2020
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