日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Discovery of Potent PDE4 Inhibitors with 3(2H)-Pyridazinone Scaffold: Synthesis, In Silico Studies and In Vitro/Vivo Evaluation

发现具有3(2H)-哒嗪酮骨架的高效PDE4抑制剂：合成、计算机模拟研究和体外/体内评价

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules31040699
Vergelli, Claudia; Crocetti, Letizia; Guerrini, Gabriella; Melani, Fabrizio; Gracia, Jordi; Buil, Maria Antonia; Garrido, Yolanda; Pagès, Lluis; Taltavull, Joan; Gavaldà, Amadeu; Calama, Elena; Giovannoni, Maria Paola
发表日期：2026
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Abnormal purinergic signaling contributes to development of renal cysts in autosomal dominant polycystic kidney disease

嘌呤能信号异常是常染色体显性多囊肾病中肾囊肿形成的原因之一。

期刊:Purinergic Signalling
影响因子:2.4
doi:10.1007/s11302-025-10127-1
Ivanov, Veniamin; Wu, Andrew; Crocetti, Letizia; Meng, Ze; Shrestha-Maskey, Puja; Liao, Tang-Dong; Adrianto, Indra; Guerrini, Gabriella; Ortiz, Pablo A; Pavlov, Tengis S
信号转导
发表日期：2026
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Special Issue "Ion Channels as a Therapeutic Target: Drug Design and Pharmacological Investigation 2.0

特刊“离子通道作为治疗靶点：药物设计和药理学研究 2.0”

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27010395
Guerrini, Gabriella; Giovannoni, Maria Paola
发表日期：2025
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Synthesis of 3-Carboxy-6-sulfamoylquinolones and Mefloquine-Based Compounds as Panx1 Blockers: Molecular Docking, Electrophysiological and Cell Culture Studies

3-羧基-6-氨磺酰喹诺酮类化合物和甲氟喹类化合物作为Panx1阻滞剂的合成：分子对接、电生理和细胞培养研究

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules30102171
Crocetti, Letizia; Giovannoni, Maria Paola; Pavlov, Tengis S; Ivanov, Veniamin; Melani, Fabrizio; Guerrini, Gabriella
细胞生物学
Cell Culture
发表日期：2025
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Anti-Inflammatory Activity of Pyrazolo[1,5-a]quinazolines

吡唑并[1,5-a]喹唑啉的抗炎活性

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules29112421
Crocetti, Letizia; Khlebnikov, Andrei I; Guerrini, Gabriella; Schepetkin, Igor A; Melani, Fabrizio; Giovannoni, Maria Paola; Quinn, Mark T
发表日期：2024
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Ion Channels as a Therapeutic Target: Drug Design and Pharmacological Investigation

离子通道作为治疗靶点：药物设计和药理学研究

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms25010171
Guerrini, Gabriella; Giovannoni, Maria Paola
发表日期：2023
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Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers

新型喹啉类Panx-1通道阻滞剂的设计、合成及药理学评价

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms24032022
Crocetti, Letizia; Giovannoni, Maria Paola; Guerrini, Gabriella; Lamanna, Silvia; Melani, Fabrizio; Bartolucci, Gianluca; Pallecchi, Marco; Paoli, Paola; Lippi, Martina; Wang, Junjie; Dahl, Gerhard
发表日期：2023
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4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABA(A) Receptor Subtype

4,5-二氢-5-氧代-吡唑并[1,5-a]噻吩并[2,3-c]嘧啶：一种新型含噻吩环的骨架。化学反应性和计算机模拟研究预测其对GABA(A)受体亚型的亲和力。

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules28073054
Crocetti, Letizia; Guerrini, Gabriella; Melani, Fabrizio; Vergelli, Claudia; Giovannoni, Maria Paola
信号转导
发表日期：2023
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New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies.

新型 Panx-1 阻滞剂：合成、生物学评价和分子动力学研究

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms23094827
Crocetti Letizia, Guerrini Gabriella, Giovannoni Maria Paola, Melani Fabrizio, Lamanna Silvia, Di Cesare Mannelli Lorenzo, Lucarini Elena, Ghelardini Carla, Wang Junjie, Dahl Gerhard
其它
发表日期：2022
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1,5,6,7-Tetrahydro-4H-indazol-4-ones as human neutrophil elastase (HNE) inhibitors

1,5,6,7-四氢-4H-吲唑-4-酮类化合物作为人中性粒细胞弹性蛋白酶（HNE）抑制剂

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2021.128380
Cantini, Niccolo; Crocetti, Letizia; Guerrini, Gabriella; Vergelli, Claudia; Schepetkin, Igor A; Pallecchi, Marco; Bartolucci, Gianluca; Quinn, Mark T; Teodori, Elisabetta; Giovannoni, Maria Paola
细胞生物学
中性粒细胞
粒细胞
发表日期：2021
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