日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gene Therapy for Cystic Fibrosis Paved the Way for the Use of Adeno-Associated Virus in Gene Therapy

囊性纤维化基因疗法为腺相关病毒在基因治疗中的应用铺平了道路

Guggino, William B; Cebotaru, Liudmila

Restoration of F508-del Function by Transcomplementation: The Partners Meet in the Endoplasmic Reticulum

通过反式互补恢复F508-del功能:互补伙伴在内质网中相遇

Bergbower, Emily Anne Smith; Sabirzhanova, Inna; Boinot, Clément; Guggino, William B; Cebotaru, Liudmila

Syntaxin 8 and the Endoplasmic Reticulum Processing of ΔF508-CFTR

Syntaxin 8 和 ΔF508-CFTR 的内质网加工

Sabirzhanova, Inna; Boinot, Clément; Guggino, William B; Cebotaru, Liudmila

Adeno-Associated Virus (AAV) gene therapy for cystic fibrosis: current barriers and recent developments

腺相关病毒(AAV)基因疗法治疗囊性纤维化:当前障碍和最新进展

Guggino, William B; Cebotaru, Liudmila

A Preclinical Study in Rhesus Macaques for Cystic Fibrosis to Assess Gene Transfer and Transduction by AAV1 and AAV5 with a Dual-Luciferase Reporter System

一项在恒河猴中进行的囊性纤维化临床前研究,旨在利用双荧光素酶报告系统评估AAV1和AAV5的基因转移和转导效率。

Guggino, William B; Benson, Janet; Seagrave, JeanClare; Yan, Ziying; Engelhardt, John; Gao, Guangping; Conlon, Thomas J; Cebotaru, Liudmila

From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

从CFTR生物学到联合药物治疗:囊性纤维化突变的扩展分类

Veit, Gudio; Avramescu, Radu G; Chiang, Annette N; Houck, Scott A; Cai, Zhiwei; Peters, Kathryn W; Hong, Jeong S; Pollard, Harvey B; Guggino, William B; Balch, William E; Skach, William R; Cutting, Garry R; Frizzell, Raymond A; Sheppard, David N; Cyr, Douglas M; Sorscher, Eric J; Brodsky, Jeffrey L; Lukacs, Gergely L

STIM1fl/fl Ksp-Cre Mouse has Impaired Renal Water Balance

STIM1fl/fl Ksp-Cre小鼠肾脏水平衡受损

Cebotaru, Liudmila; Cebotaru, Valeriu; Wang, Hua; Arend, Lois J; Guggino, William B

CFTR Controls the Activity of NF-κB by Enhancing the Degradation of TRADD

CFTR通过增强TRADD的降解来控制NF-κB的活性。

Wang, Hua; Cebotaru, Liudmila; Lee, Ha Won; Yang, QingFeng; Pollard, Bette S; Pollard, Harvey B; Guggino, William B

Transcomplementation by a truncation mutant of cystic fibrosis transmembrane conductance regulator (CFTR) enhances ΔF508 processing through a biomolecular interaction

囊性纤维化跨膜传导调节因子 (CFTR) 截短突变体的反式互补作用通过生物分子相互作用增强 ΔF508 的加工。

Cebotaru, Liudmila; Woodward, Owen; Cebotaru, Valeriu; Guggino, William B

Future directions in early cystic fibrosis lung disease research: an NHLBI workshop report

囊性纤维化早期肺病研究的未来方向:美国国家心肺血液研究所研讨会报告

Ramsey, Bonnie W; Banks-Schlegel, Susan; Accurso, Frank J; Boucher, Richard C; Cutting, Garry R; Engelhardt, John F; Guggino, William B; Karp, Christopher L; Knowles, Michael R; Kolls, Jay K; LiPuma, John J; Lynch, Susan; McCray, Paul B Jr; Rubenstein, Ronald C; Singh, Pradeep K; Sorscher, Eric; Welsh, Michael