日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Comparative assessment of the transduction efficiency and safety associated with the delivery of AAV9-GFP vector via lumbar puncture to cynomolgus macaques with and without anti-AAV9 pre-existing antibodies

对通过腰椎穿刺向有和没有抗 AAV9 预先存在抗体的食蟹猴输送 AAV9-GFP 载体的转导效率和安全性进行比较评估

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:
doi:10.1016/j.omtm.2024.101371
Ghiabe H Guibinga, Janet Do, Binh Chu, Yin Gu, Rie Kikkawa, Xiaoguang Li, Fatih Ozsolak, Timothy MacLachlan
信号转导
NAL1
发表日期：2024
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Prenatal AAV9-GFP administration in fetal lambs results in transduction of female germ cells and maternal exposure to virus

产前给羊羔注射 AAV9-GFP 可导致雌性生殖细胞的转导和母体接触病毒

期刊:Molecular Therapy-Methods & Clinical Development
影响因子:
doi:10.1016/j.omtm.2024.101263
Beltran Borges, Antonia Varthaliti, Marisa Schwab, Maria T Clarke, Christopher Pivetti, Nalin Gupta, Cathryn R Cadwell, Ghiabe Guibinga, Shirley Phillips, Tony Del Rio, Fatih Ozsolak, Denise Imai-Leonard, Lingling Kong, Diana J Laird, Akos Herzeg, Charlotte J Sumner, Tippi C MacKenzie
微生物学
细胞生物学
其它细胞
发表日期：2024
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Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques

鞘内注射sc-AAV9-CB-GFP：食蟹猴单次给药后以全身分布为主

期刊:Toxicologic Pathology
影响因子:1.8
doi:10.1177/01926233221101309
Meseck, Emily K; Guibinga, Ghiabe; Wang, Stephen; McElroy, Cameron; Hudry, Eloise; Mansfield, Keith
GFP
发表日期：2022
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Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms

建立猪流感攻击模型以评估单克隆抗体递送平台

期刊:Journal of Immunology
影响因子:3.6
doi:10.4049/jimmunol.2000429
Adam McNee, Trevor R F Smith, Barbara Holzer, Becky Clark, Emily Bessell, Ghiabe Guibinga, Heather Brown, Katherine Schultheis, Paul Fisher, Stephanie Ramos, Alejandro Nunez, Matthieu Bernard, Simon Graham, Veronica Martini, Tiphany Chrun, Yongli Xiao, John C Kash, Jeffery K Taubenberger, Sarah Elli
免疫
流感
ELISA
ICC
IHC
Human
发表日期：2020
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Protection against Borreliella burgdorferi infection mediated by a synthetically engineered DNA vaccine

通过合成 DNA 疫苗预防伯氏疏螺旋体感染

期刊:Human Vaccines & Immunotherapeutics
影响因子:
doi:10.1080/21645515.2020.1789408
Ghiabe H Guibinga, Bikash Sahay, Heather Brown, Neil Cooch, Jing Chen, Jian Yan, Charles Reed, Meerambika Mishra, Bryan Yung, Holly Pugh, Katherine Schultheis, Rianne N Esquivel, David B Weiner, Laurent H Humeau, Kate E Broderick, Trevor R F Smith
信号转导
发表日期：2020
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Striatal neurodevelopment is dysregulated in purine metabolism deficiency and impacts DARPP-32, BDNF/TrkB expression and signaling: new insights on the molecular and cellular basis of Lesch-Nyhan Syndrome

嘌呤代谢缺陷导致纹状体神经发育失调，影响 DARPP-32、BDNF/TrkB 表达和信号传导：关于莱施-尼汉综合征分子和细胞基础的新见解

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0096575
Ghiabe-Henri Guibinga, Nikki Barron, William Pandori
代谢
信号转导
神经
其它细胞
WB
Developmental Biology
Neuroscience
发表日期：2014
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Deficiency of the purine metabolic gene HPRT dysregulates microRNA-17 family cluster and guanine-based cellular functions: a role for EPAC in Lesch-Nyhan syndrome

嘌呤代谢基因 HPRT 的缺乏导致 microRNA-17 家族簇和鸟嘌呤类细胞功能失调：EPAC 在 Lesch-Nyhan 综合征中的作用

期刊:Human Molecular Genetics
影响因子:3.1
doi:10.1093/hmg/ddt298
Ghiabe-Henri Guibinga, Fiona Murray, Nikki Barron, William Pandori, Gorjan Hrustanovic
代谢
其它细胞
发表日期：2013
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HPRT-deficiency dysregulates cAMP-PKA signaling and phosphodiesterase 10A expression: mechanistic insight and potential target for Lesch-Nyhan Disease?

HPRT 缺乏会导致 cAMP-PKA 信号传导和磷酸二酯酶 10A 表达失调：莱施-尼汉病的机制见解和潜在靶点？

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0063333
Ghiabe-Henri Guibinga, Fiona Murray, Nikki Barron
信号转导
GPCR/Calcium/cAMP
发表日期：2013
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MicroRNA-mediated dysregulation of neural developmental genes in HPRT deficiency: clues for Lesch-Nyhan disease?

HPRT 缺乏症中 microRNA 介导的神经发育基因失调：莱施-尼汉氏病的线索？

期刊:Human Molecular Genetics
影响因子:3.2
doi:10.1093/hmg/ddr495
Guibinga, Ghiabe-Henri; Hrustanovic, Gorjan; Bouic, Kathryn; Jinnah, Hyder A; Friedmann, Theodore
HPRT
发育与干细胞
神经科学
发表日期：2012
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HPRT deficiency coordinately dysregulates canonical Wnt and presenilin-1 signaling: a neuro-developmental regulatory role for a housekeeping gene?

HPRT 缺陷会协调失调典型的 Wnt 和早老素-1 信号传导：管家基因的神经发育调节作用？

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0016572
Tae Hyuk Kang, Ghiabe-Henri Guibinga, H A Jinnah, Theodore Friedmann
神经
Wnt/β-Catenin
发表日期：2011
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