Physiologically based pharmacokinetic model of sodium-glucose cotransporter 2 inhibitors predicted pharmacokinetics and pharmacodynamics to explore dosage regimen for patients with type 2 diabetes mellitus and renal insufficiency
基于生理的钠-葡萄糖协同转运蛋白2抑制剂药代动力学模型预测了其药代动力学和药效学,以探索2型糖尿病合并肾功能不全患者的给药方案。
期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1520268
Guo, Guimu; Ke, Meng; Xu, Jianwen; Wu, Wanhong; Chen, Jiarui; Ke, Chengjie; Huang, Pinfang; Lin, Cuihong