日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Off-target binding of the histone deacetylase inhibitor vorinostat to carbonic anhydrase II and IX

组蛋白去乙酰化酶抑制剂伏立诺他与碳酸酐酶II和IX的非靶向结合

Gulkis, Mitchell C; Hodgkinson, James T; Sele, Céleste P; Knecht, Wolfgang; McKenna, Robert; Fisher, S Zoë

Unfilled gaps by polβ lead to aberrant ligation by LIG1 at the downstream steps of base excision repair pathway

polβ 未填补的缺口会导致 LIG1 在碱基切除修复途径下游步骤中发生异常连接。

Gulkis, Mitchell; Martinez, Ernesto; Almohdar, Danah; Çağlayan, Melike

Probing the mechanism of nick searching by LIG1 at the single-molecule level

在单分子水平上探究LIG1寻找缺口的机制

Chatterjee, Surajit; Chaubet, Loïc; van den Berg, Aafke; Mukhortava, Ann; Almohdar, Danah; Ratcliffe, Jacob; Gulkis, Mitchell; Çağlayan, Melike

Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in the Base Excision Repair Pathway

polβ/XRCC1 相互作用变体对碱基切除修复途径中 DNA 连接酶 IIIα 缺口修复效率的影响

Danah Almohdar, Mitchell Gulkis, Abigail Ortiz, Qun Tang, Robert W Sobol, Melike Çağlayan

Molecular editing of NSC-666719 enabling discovery of benzodithiazinedioxide-guanidines as anticancer agents

NSC-666719 的分子编辑使苯并二噻嗪二氧化物胍被发现作为抗癌剂

Vajja Krishna Rao, Subarno Paul, Mitchell Gulkis, Zhihang Shen, Haritha Nair, Amandeep Singh, Chenglong Li, Arun K Sharma, Melike Çağlayan, Chinmay Das, Biswajit Das, Chanakya N Kundu, Satya Narayan, Sankar K Guchhait

Structures of LIG1 provide a mechanistic basis for understanding a lack of sugar discrimination against a ribonucleotide at the 3'-end of nick DNA

LIG1的结构为理解其对缺口DNA 3'末端核糖核苷酸缺乏糖类选择性提供了机制基础。

Balu, Kanal Elamparithi; Gulkis, Mitchell; Almohdar, Danah; Çağlayan, Melike

Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes

人类蟾蜍病毒 1 的结构表征:受体结合和内体 pH 诱导的变化

Mitchell Gulkis, Mengxiao Luo, Paul Chipman, Mario Mietzsch, Maria Söderlund-Venermo, Antonette Bennett, Robert McKenna

Structures of LIG1 that engage with mutagenic mismatches inserted by polβ in base excision repair

在碱基切除修复中,LIG1 的结构与 polβ 插入的致突变错配有关

Qun Tang, Mitchell Gulkis, Robert McKenna, Melike Çağlayan

Implications of the ammonia distribution on Jupiter from 1 to 100 bars as measured by the Juno microwave radiometer

朱诺号微波辐射计测量的木星表面1至100巴范围内氨分布的意义

Ingersoll, Andrew P; Adumitroaie, Virgil; Allison, Michael D; Atreya, Sushil; Bellotti, Amadeo A; Bolton, Scott J; Brown, Shannon T; Gulkis, Samuel; Janssen, Michael A; Levin, Steven M; Li, Cheng; Li, Liming; Lunine, Jonathan I; Orton, Glenn S; Oyafuso, Fabiano A; Steffes, Paul G