日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Histone deacetylase (HDAC) inhibitor kinetic rate constants correlate with cellular histone acetylation but not transcription and cell viability

组蛋白去乙酰化酶(HDAC)抑制剂的动力学速率常数与细胞组蛋白乙酰化相关,但与转录和细胞活力无关。

Benjamin E L Lauffer ,Robert Mintzer, Rina Fong, Susmith Mukund, Christine Tam, Inna Zilberleyb, Birgit Flicke, Allegra Ritscher, Grazyna Fedorowicz, Roxanne Vallero, Daniel F Ortwine, Janet Gunzner, Zora Modrusan, Lars Neumann, Christopher M Koth, Patrick J Lupardus, Joshua S Kaminker, Christopher E Heise, Pascal Steiner

GDC-0449-a potent inhibitor of the hedgehog pathway

GDC-0449-一种强效的 Hedgehog 通路抑制剂

Kirk D Robarge, Shirley A Brunton, Georgette M Castanedo, Yong Cui, Michael S Dina, Richard Goldsmith, Stephen E Gould, Oivin Guichert, Janet L Gunzner, Jason Halladay, Wei Jia, Cyrus Khojasteh, Michael F T Koehler, Karen Kotkow, Hank La, Rebecca L Lalonde, Kevin Lau, Leslie Lee, Derek Marshall, Jam

Liposomal packaging generates Wnt protein with in vivo biological activity

脂质体包装可生成具有体内生物活性的Wnt蛋白。

Morrell, Nathan T; Leucht, Philipp; Zhao, Ludan; Kim, Jae-Beom; ten Berge, Derk; Ponnusamy, Karthik; Carre, A Lyonel; Dudek, Henryk; Zachlederova, Marie; McElhaney, Michael; Brunton, Shirley; Gunzner, Janet; Callow, Marinella; Polakis, Paul; Costa, Mike; Zhang, Xiaoyan M; Helms, Jill A; Nusse, Roel